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http://dx.doi.org/10.1016/j.jaad.2015.04.042 | DOI Listing |
AAPS PharmSciTech
January 2025
Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University (MRSPTU), Bathinda, 151001, Punjab, India.
Microneedles (MNs) appear as a transformative and minimally invasive platform for transdermal drug delivery, representing a highly promising strategy in wound healing therapeutics. This technology, entailing the fabrication of micron-scale needle arrays, enables the targeted and efficient delivery of bioactive agents into the epidermal and dermal layers without inducing significant pain or discomfort. The precise penetration of MNs facilitates localized and sustained drug release, which significantly enhances tissue regeneration and accelerates wound closure.
View Article and Find Full Text PDFJ Biomech
November 2024
Department of Orthopedics and Rehabilitation, The University of Iowa, United States; Department of Biomedical Engineering, The University of Iowa, United States; Department of Industrial and Systems Engineering, The University of Iowa, United States.
A CT-based method for objectively assessing fracture severity was previously developed and validated to address poor reliability in existing subjective fracture classification systems. The method involved quantifying the energy involved in creating a fracture. However, clinical utility of the method was hindered by reliance upon an intact contralateral CT and lengthy analysis time (8-10 h).
View Article and Find Full Text PDFBraz Oral Res
January 2025
Universidade Federal de Santa Maria - UFSM, School of Dentistry, Department of Restorative Dentistry, Santa Maria, RS, Brazil.
This study aimed to evaluate the effects of fiberglass posts on fracture behavior in endodontically treated teeth (ETT) restored with composite veneers. Adult patients who had endodontically treated anterior teeth restored with composite veneers, with or without fiberglass posts, were divided into the case (with fractured teeth) and control (without fractured teeth) groups. All fracture patterns were sorted by a 6-point scoring system: 0, no fracture; 1, veneer buccal fracture; 2, incisal edge fracture; 3, coronal middle-third fracture; 4, coronal cervical fracture; 5, coronal and root fracture; and 6, root fracture.
View Article and Find Full Text PDFBiomedicines
December 2024
Clinical Diagnosis and Investigation (Rognidan), National Institute of Ayurveda, Jaipur 302002, India.
Wound and injury healing processes are intricate and multifaceted, involving a sequence of events from coagulation to scar tissue formation. Effective wound management is crucial for achieving favorable clinical outcomes. Understanding the cellular and molecular mechanisms underlying wound healing, inflammation, and regeneration is essential for developing innovative therapeutics.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2024
School of Civil & Environmental Engineering, and Construction Management, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
In hot and humid work environments, construction workers can experience heat stress and heat-related illnesses (HRIs). While several studies have investigated engineering and administrative control methods to prevent certain heat stress risk factors, a comprehensive understanding of all existing risk factors and their corresponding control strategies is still lacking. It is crucial to identify gaps in current control strategies and develop a safety management framework for effective heat stress control by implementing existing measures.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!