AI Article Synopsis
- General paralysis of the insane (GPI), linked to syphilis, was a common psychiatric issue before becoming rare, but its resurgence is expected due to a rise in syphilis cases.
- Early diagnosis and treatment of GPI are crucial to prevent irreversible damage, highlighting the importance of recognizing its psychiatric and neurological symptoms.
- A historical study of 105 GPI patients from a Dutch psychiatric hospital between 1924-1954 provides detailed insights into the clinical features of this debilitating condition.
Article Abstract
General paralysis of the insane (GPI) or dementia paralytica was once a fatal complication of syphilitic infection and a major reason for psychiatric hospitalization. Nowadays, physicians consider GPI to be exceptional. It should be noted, however, that syphilis re-emerged worldwide at the turn of the 20th to 21st century and a revival of GPI can, therefore, be expected. Advanced diagnosis is crucial in that treatment in the early, inflammatory phase is warranted before irreversible tissue damage occurs. Therefore, a renewed clinical awareness of the broad spectrum of psychiatric and neurologic signs and symptoms of GPI is needed. In this historical cohort study, comprising 105 patients with GPI admitted to the Dutch Vincent van Gogh Psychiatric Hospital in the period 1924-1954, the clinical presentation of this invalidating disorder is investigated and described in detail.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000435835 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!