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Safety and efficacy of tirofiban in the endovascular treatment of intracranial aneurysms: a systematic evaluation and meta-analysis.
Neurosurg Rev
January 2025
Hengyang Key Laboratory of Hemorrhagic Cerebrovascular Disease, Department of Neurosurgery, the Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421000, Hunan, China.
Patients with intracranial aneurysms (IA) undergoing endovascular treatment face varying risks and benefits when tirofiban is used for thromboprophylaxis during surgery. Currently, there is a lack of high-level evidence summarizing this information. This study aims to conduct a systematic review and meta-analysis to evaluate the efficacy and safety of tirofiban during endovascular treatment of IA.
View Article and Find Full Text PDFAssociation between sleep quality and serum biomarkers among long-term hot spring bathers: a cross-sectional study.
Int J Biometeorol
January 2025
West China School of Public Health and West China Fourth Hospital, Sichuan University, Renmin South Road, Chengdu, 610041, China.
Previous studies investigating the influence of hot spring bathing on sleep quality have predominantly focused on the short-term effects through questionnaire surveys without blood collection for biochemical tests. Here, we undertook a comprehensive investigation of the long-term health effects of hot spring bathing among the residents of Hot Spring Village. A total of 140 participants were enrolled, and their demographic characteristics and the patterns of hot spring bathing were obtained via face-to-face interview, and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI).
View Article and Find Full Text PDFPhotothermal antimicrobial guar gum hydrogel cross-linked by bioactive small molecule lysine for infected wound healing.
Int J Biol Macromol
January 2025
Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430070, China. Electronic address:
The healing of bacteria-infected wounds has long posed a significant clinical challenge. Traditional hydrogel wound dressings often lack self-healing properties and effective antibacterial characteristics, making wound healing difficult. In this study, a bioactive small molecule cross-linking agent 4-FPBA/Lys/4-FPBA (FLF) composed of 4-formylphenylboronic acid (4-FPBA) and lysine (Lys) was utilized to cross-link guar gum (GG) and a tannic acid/iron (TA/Fe) chelate through multiple dynamic bonds, leading to the formation of a novel self-healing hydrogel dressing GG-FLF/TA/Fe.
View Article and Find Full Text PDFConstructing an Organic-Inorganic Hybrid Solid-Electrolyte Interface In Situ via an Organo-Polysulfide Electrolyte Additive for Lithium-Sulfur Batteries.
ACS Appl Mater Interfaces
January 2025
School of Material Science and Engineering, Jiangsu Collaborative Innovation Center for Photovoltaic Science and Engineering, Jiangsu Province Cultivation Base for State Key Laboratory of Photovoltaic Science and Technology, Changzhou University, Changzhou 213164, China.
Lithium (Li) metal's extremely high specific energy and low potential make it critical for high-performance batteries. However, uncontrolled dendrite growth and an unstable solid-electrolyte interphase (SEI) during repeated cycling still seriously hinder its practical application in Li metal batteries. Herein, we demonstrate a facile and effective approach to fabricate a flexible and robust hybrid SEI layer using two kinds of organo-polysulfides with different sulfur chain lengths [bis(3-(triethoxysilyl)propyl)disulfide (Si-O-2S) and bis(3-(triethoxysilyl)propyl)tetrasulfide (Si-O-4S)] as the additives in the electrolyte.
View Article and Find Full Text PDFPredicting Individual Pain Sensitivity Using a Novel Cortical Biomarker Signature.
JAMA Neurol
January 2025
Department of Neural and Pain Sciences, University of Maryland School of Dentistry, Baltimore.
Importance: Biomarkers would greatly assist decision-making in the diagnosis, prevention, and treatment of chronic pain.
Objective: To undertake analytical validation of a sensorimotor cortical biomarker signature for pain consisting of 2 measures: sensorimotor peak alpha frequency (PAF) and corticomotor excitability (CME).
Design, Setting, And Participants: This cohort study at a single center (Neuroscience Research Australia) recruited participants from November 2020 to October 2022 through notices placed online and at universities across Australia.
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