Conventional functional magnetic resonance imaging (fMRI) studies on motor feedback employ periodical blocked paradigm which does not allow frequency analysis of brain activity. Here, we carried out an fMRI study by using a continuous paradigm, that is, continuous (8 min) feedback of finger force. Borrowing an analytic method widely used in resting-state fMRI studies, that is, regional homogeneity (ReHo), we compared the local synchronization in some subfrequency bands between real and sham feedback, and the subbands were defined as Slow-6 (0.0-0.01 Hz), Slow-5 (0.01-0.027 Hz), Slow-4 (0.027-0.073 Hz), Slow-3 (0.073-0.198 Hz), and Slow-2 (0.198-0.25 Hz). Our results revealed that the five subfrequency bands of brain activity contributed to the changes of ReHo between real and sham feedback differently, and, more importantly, the changes in basal ganglia were only manifested in Slow-6, implicating the fact that ReHo in ultraslow band may be associated with the functional significance of BG, that is, motor control. These findings provide novel insights into the neural substrate underlying motor feedback, and properties of the ultraslow band of local synchronization deserve more attention in future explorations.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477192 | PMC |
| http://dx.doi.org/10.1155/2015/273126 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Replicase components and the untranslated region of RNA2 synergistically regulate pathogenicity differentiation among different isolates of cucumber mosaic virus.
Int J Biol Macromol
January 2025
Department of Plant Pathology, College of Plant Protection, Shandong Agricultural University, Shandong Province Key Laboratory of Agricultural Microbiology, Tai'an 271018, PR China. Electronic address:
Changes in critical sites of virus-encoded protein or cis-acting element generally determine pathogenicity differentiation among different isolates of the same plant virus. Cucumber mosaic virus (CMV) isolates, which exhibit the most extensively known host range, demonstrate notable pathogenicity differentiation. This study focuses on the severe isolate CMV and mild isolate CMV, both affecting several species within the Solanaceae family, to identify the key factors regulating pathogenicity differentiation.
View Article and Find Full Text PDFCondensation and Synchronization in Aligning Chiral Active Matter.
Phys Rev Lett
December 2024
Center for Soft Condensed Matter Physics and Interdisciplinary Research, Soochow University, Suzhou 215006, China.
We show that spontaneous density segregation in dense systems of aligning circle swimmers is a condensation phenomenon at odds with the phase separation scenarios usually observed in two-dimensional active matter. The condensates, which take the form of vortices or rotating polar packets, can absorb a finite fraction of the particles in the system, and keep a finite or slowly growing size as their mass increases. Our results are obtained both at particle and continuous levels.
View Article and Find Full Text PDFIncidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or Ductal Carcinoma In Situ in Patients Diagnosed with Flat Epithelial Atypia by Core Needle Biopsy (TBCRC 034).
Ann Surg Oncol
January 2025
Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
Background: Flat epithelial atypia (FEA), a rare breast proliferative lesion, is often diagnosed following core biopsy (CB) of mammographic microcalcifications. In the prospective multi-institution TBCRC 034 trial, we investigate the upgrade rate to ductal carcinoma in situ (DCIS) or invasive cancer following excision for patients diagnosed with FEA on CB.
Patients And Methods: Patients with a breast imaging reporting and data system (BI-RADS) ≤ 4 imaging abnormality and a concordant CB diagnosis of FEA were identified for excision.
Beta-band oscillations and spike-local field potential synchronization in the motor cortex are correlated with movement deficits in an exercise-induced fatigue mouse model.
Cogn Neurodyn
December 2025
Exercise Physiology and Neurobiology Lab, College of Physical Education and Sports, Beijing Normal University, No. 19, Xinjiekou Street, Beijing, 100875 China.
Fatigue, a complex and multifaceted symptom, profoundly influences quality of life, particularly among individuals suffering from chronic medical conditions or neurological disorders. This symptom not only exacerbates existing conditions but also hinders daily functioning, thereby perpetuating a vicious cycle of worsening symptoms and reduced physical activity. Given the pivotal role of the motor cortex (M1) in coordinating and executing voluntary movements, understanding how the cortex regulates fatigue is crucial.
View Article and Find Full Text PDFThe METACER national cohort study of brain metastases in gastrointestinal cancers prospectively establishes prognostic factors.
J Neurooncol
January 2025
Department of Hepatology and Gastro-enterology, CHU de Poitiers, Poitiers, France.
Purpose: Availability data are scarce and primarily retrospective in patients with brain metastasis (BM) from gastrointestinal (GI) cancers. The objective of this cohort was to determine prognostic factors for survival outcomes in patients with BM from GI cancers.
Methods: METACER is a national multicentric prospective cohort study which included patients with BM diagnosis during a histologically proven digestive cancer follow-up between 2010 and 2014.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!