The effect of lycopene on serum nitrate-nitrite levels was investigated in diabetic rats. In this investigation, 28 Wistar rats were divided into 4 groups, each of seven rats. These groups were control group, diabetes group, diabetes-lycopene group and lycopene group. The concentration of nitrite and nitrate was detected at high levels in diabetes group, diabetes-lycopene group and lycopene group as compared with the control group (P<0.05). Especially, the increase in the levels of nitrate in diabetes group and lycopene group was statistically significant when compared with diabetes-lycopene group and control group (P<0.05). In addition, we also determined the proportion of nitrite/nitrate for nitric oxide radical formation. Therefore, it is important to investigate the recovery and stability of nitrite and nitrate in samples. As a result of this study, it was observed that the amounts of nitrate and nitrite increased due to oxidative stress in diabetes and also application of antioxidant lycopene caused an increase in the amounts of nitrate and nitrite levels.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502153 | PMC |
| http://dx.doi.org/10.4103/0250-474x.159676 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association between serum carotenoids levels and severe headache or migraine in adults: a cross-sectional study from NHANES.
Front Nutr
January 2025
Department of Anesthesiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Background: Carotenoids are well-established for their potent antioxidant properties; however, their potential association with severe headaches or migraines remains largely unexamined. This study was conducted to explore the relationship between serum carotenoid levels and the prevalence of severe headaches or migraines within the US population.
Methods: We utilized data from the 2001-2004 National Health and Nutrition Examination Survey (NHANES), which comprised a total of 8,910 participants.
Enhancing growing rabbit heat stress resilience through dietary supplementation with natural antioxidants.
BMC Vet Res
January 2025
Department of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
Animal husbandry development is influenced by various factors, with heat stress (HS) being a significant factor. The aim of this experiment was to explore the potential of natural antioxidants such as vitamin C (VITC), vitamin E (VITE), lycopene (LYC), and allicin (AL) in enhancing growth, immune function and maintaining the redox status of fattening rabbits under HS. Male weaning rabbits (n = 150, 5 weeks of age) were randomly assigned to 5 groups.
View Article and Find Full Text PDFAssociation of serum lycopene with low-frequency hearing loss in adults in their 70s based on NHANES database.
Sci Rep
January 2025
Department of Otolaryngology, The Affiliated Jiangning Hospital of Nanjing Medical University, 169 Hushan Road, Jiangning District, Nanjing, 211100, Jiangsu, China.
Age-related hearing loss is the third most common health condition affecting elderly individuals. The relationship between lycopene in blood and sensorineural hearing loss in elderly adults has rarely been reported. This study aimed to elucidate the connection between serum lycopene levels and sensorineural hearing loss among elderly individuals.
View Article and Find Full Text PDF[The protective effect of lycopene on lung oxidative damage induced by atmospheric fine particulate matter exposure in rats].
Wei Sheng Yan Jiu
November 2024
Shanghai University of Medicine & Health Sciences, Shanghai 200237, China.
Objective: To investigate the protective effect of lycopene on lung oxidative damage induced by atmospheric fine particulate matter(PM_(2.5)) in rats.
Methods: Sixty 7-week-old male Sprague-Dawley rats were randomly divided into six groups: normal control group, PM_(2.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!