Objective: To examine the risk of pregnancy loss in women with rheumatoid arthritis (RA).
Methods: Cumulative numbers of early miscarriages (before gestational Week 12), late miscarriages (weeks 12-22), and stillbirths reported to the Medical Birth Registry of Norway in the period 1999-2009.
Results: There were 1578 women with RA and 411,130 reference women included in the study. Relative risks of early and late miscarriage in women with RA versus references were 1.2 (95% CI 1.1-1.3) and 1.4 (95% CI 1.1-1.7), respectively. There was no difference in stillbirth.
Conclusion: The risk of miscarriage was slightly higher among women with RA than in references.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3899/jrheum.141553 | DOI Listing |
BMJ Case Rep
January 2025
Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and haemophagocytic lymphohistiocytosis (HLH) are rare but severe immune-mediated diseases with overlapping clinical manifestations. We present a case of a woman in her late 40s with rheumatoid arthritis who developed DRESS/HLH overlap syndrome after starting hydroxychloroquine and leflunomide therapy. Despite corticosteroid treatment, her condition worsened, necessitating etoposide therapy.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
S.C. Reumatologia, ASL3 Genovese, Genoa, Italy.
Introduction: Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy associated with cutaneous psoriasis (PsO), first defined by Moll and Wright. Initially perceived as relatively benign, PsA is now recognized for its chronic, progressive, and destructive nature, significantly impacting patients' quality of life, similar to Rheumatoid Arthritis (RA). Globally, PsA represents about 20% of cases in early arthritis clinics, posing diagnostic and management challenges.
View Article and Find Full Text PDFAnn Rheum Dis
January 2025
Academic Department of Rheumatology, Kings College London, London, UK. Electronic address:
Multiple clinical trials for rheumatoid arthritis (RA) prevention have been completed. Here, we set out to report on the lessons learnt from these studies. Researchers who conducted RA prevention trials shared the background, rationale, approach and outcomes and evaluated the lessons learnt to inform the next generation of RA prevention trials.
View Article and Find Full Text PDFJ Am Podiatr Med Assoc
January 2025
‖Pain Therapy Associates, Schaumburg, IL.
Background: Although an association between peripheral nerve entrapment issues and rheumatoid arthritis (RA) has been found, research has generally focused solely on nerve entrapment in the upper or lower extremity individually rather than on the consideration of nerve entrapment simultaneously in the upper and lower extremities. In addition, most of these studies have used small sample sizes. The aim of this study was to evaluate the incidence of carpal tunnel syndrome (CTS) and tarsal tunnel syndrome (TTS) concurrently in patients with RA using a relatively large sample size.
View Article and Find Full Text PDFEur Cardiol
December 2024
REMEDY Center for Treatment of Rheumatic and Musculoskeletal Diseases, Diakonhjemmet Hospital Oslo, Norway.
This review examines the cardiovascular risks associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs), both traditional NSAIDs and cyclooxygenase-2 selective inhibitors (COXIBs). It describes the history of traditional NSAIDs and the development of COXIBs to explain why their cardiovascular side effects were unnoticed for many decades. Further, the review presents the mechanism of action of NSAIDs, to elucidate the possible underlying basis for why they are associated with an increased risk of cardiovascular disease.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!