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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503781 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133344 | PLOS |
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Dog-Owner Relationship and Its Association with Social Cognition in French Bulldogs.
Animals (Basel)
December 2024
Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Groblje 3, 1230 Domžale, Slovenia.
Our understanding of social cognition in brachycephalic dog breeds is limited. This study focused specifically on French Bulldogs and hypothesized that a closer relationship between dog and owner would improve the dogs' understanding of nonverbal cues, particularly pointing gestures. To investigate this, we tested twenty-six dogs and their owners in a two-way object choice test in which the familiar person pointed to the bowl.
View Article and Find Full Text PDFAn Implementation Research Study on Uterotonics Use Patterns and Heat-stable Carbetocin Acceptability and Safety for Prevention of Postpartum Hemorrhage in Nigeria.
Int J MCH AIDS
September 2024
Global Resources for Health West and Central Africa & Country Programs Nigeria, Clinton Health Access Initiative, Maitama, Abuja, Nigeria.
Background And Objective: The burden of maternal mortality attributable to postpartum hemorrhage (PPH) remains high in Nigeria. Currently, oxytocin, and misoprostol, which are largely of suboptimal quality, are used for PPH prevention and treatment. Heat-stable carbetocin (HSC) is a viable uterotonic option for PPH prevention in a setting like Nigeria where compromised supply and cold chain systems result in the preponderance of poor-quality oxytocin and suboptimal PPH management.
View Article and Find Full Text PDFDisengagement of somatostatin neurons from lateral septum circuitry by oxytocin and vasopressin restores social-fear extinction and suppresses aggression outbursts in Prader-Willi syndrome model.
Biol Psychiatry
October 2023
Institut de Génomique Fonctionnelle, University of Montpellier, INSERM, CNRS, France. Electronic address:
Article Synopsis
- The study investigates how the symptoms of social signal processing in Prader-Willi Syndrome (PWS) can be influenced by neuropeptides oxytocin (OXT) and vasopressin (AVP), particularly focusing on their effects in the lateral septum (LS) of the brain.
- It uses a mouse model with a knockout of the Magel2 gene, employing various experimental techniques to observe the role of OXT and AVP in social-fear situations and identify neuronal pathways involved.
- The findings reveal that deficits in OXT and AVP signaling lead to disrupted social-fear responses by affecting certain inhibitory neurons in the LS, providing insights that could pave the way for new treatment strategies for autism spectrum disorders.
Severe hyponatremia in obstetrics: Presentations and outcome. Retrospective cohort over 10 years.
Int J Gynaecol Obstet
October 2024
Obstetrics and Gynecology Department, Epsom and St. Helier University Hospitals NHS Trust, Epsom, UK.
Hyponatremia in labor and the postpartum period is generally underreported. In this study we aimed to identify attributable causes of severe hyponatremia in an obstetric population and define maternal outcomes. This was a retrospective cohort study, in a single center over a period of 10 years.
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