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Similar Publications

Onychomycosis caused by Aspergillus species belonging to section Circumdati.

J Dermatol

December 2024

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

We encountered two cases of onychomycosis caused by Aspergillus (A.) subramanianii and A. sclerotiorum.

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Article Synopsis
  • - Onychomycosis is a tough fungal nail infection that can lead to further complications, prompting the need for accurate pathogen identification through testing to enhance treatment effectiveness.
  • - A study analyzing over 710,000 patient records from 2015-2024 utilized PCR testing, revealing a wider range of pathogens than previously known, particularly showing that non-dermatophyte molds and yeasts are significant in female patients and older adults.
  • - The use of advanced molecular diagnostics allows for quicker and more precise identification of the fungi causing onychomycosis, which can lead to better treatment choices and improved healthcare outcomes.
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Article Synopsis
  • Onychomycosis is a fungal infection of the nails that frequently affects diabetic patients, leading to potential complications and decreased quality of life.
  • The study aimed to evaluate the prevalence and characteristics of onychomycosis in diabetic individuals compared to healthy controls in Nigeria.
  • Findings indicated that the prevalence among diabetics was 45.3% and included various types of fungi, with the most common being dermatophytes, non-dermatophytes, and Candida species, highlighting a significant link between foot ulcers and the infection.
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The genus Aspergillus consists of a vast number of medically and environmentally relevant species. Aspergillus species classified in series Versicolores are ubiquitous in the environment and include the opportunistic pathogen Aspergillus sydowii, which is associated with onychomycosis and superficial skin infections. Despite frequent clinical reports of A.

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Onychomycosis is an under-recognized healthcare burden. Despite the risk of misdiagnosis, confirmatory laboratory testing is under-utilized. Histopathologic examination with polymerase chain reaction (PCR) is currently the most effective diagnostic method; it offers direct detection and identification of a fungal invasion.

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