AI Article Synopsis
- - A study analyzed the outcomes of 53 patients with severe mental illness undergoing antiretroviral therapy (ART) for advanced HIV, revealing various diagnoses such as psychosis secondary to HIV and depression with psychotic features.
- - After 96 weeks, a significant portion of patients in care showed good responses to ART, with 85% achieving a viral load under 400 copies/mL and 76% under 25 copies/mL, while their median CD4 count improved from 66 to 307/mm(3).
- - The findings highlighted that the initial 6 months were crucial for retaining patients in care, with a notable number (27 out of 34) discontinuing their antipsychotic medications during the
Article Abstract
A retrospective cohort analysis was performed to describe outcomes and retention in care on antiretroviral therapy (ART) of 53 patients with severe mental illness (SMI). Diagnoses were psychosis secondary to HIV (24 patients), psychosis not otherwise specified (12), mania with or without psychosis (9), depression with psychotic features (4), and schizophrenia and bipolar mood disorder (2 each). The median baseline CD4 count was 66/mm(3) and viral load was 5.4 log10 copies/mL. Thirteen (25%) patients were lost to follow-up (10 within 6 months), 3 were transferred out, and 3 died. By week 96, 29 (85%) of 34 (64%) patients still in care had a viral load <400 copies/mL and 26 (76%) a viral load <25 copies/mL. Median CD4 count increased to 307/mm(3). Twenty-seven of 34 patients discontinued antipsychotic medication. Patients with SMI and advanced HIV infection responded well to ART. The first 6 months was important for retention in care.
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| http://dx.doi.org/10.1177/2325957415593634 | DOI Listing |
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