Objective: To describe the characteristics and prognosis of subjects classified as frail in a large sample of Mexican community-dwelling elderly.
Materials And Methods: An eleven-year longitudinal study of 5 644 old adults participating in the Mexican Health and Aging Study (MHAS). Frailty was defined by meeting at least three of the following criteria: weight loss, weakness, exhaustion, slow walking speed and low physical activity. The main outcomes were incident disability and death. Multiple covariates were used to test the prognostic value of frailty.
Results: Thirty-seven percent of participants (n= 2 102) met the frailty criteria. Frail participants were significantly older, female, less educated, with more chronic disease, lower income, and poorer self-reported health status, in comparison with their non-frail counterparts. Frailty was a predictor both for disability activities of daily living and for mortality.
Conclusion: After a follow-up of more than ten years, the phenotype of frailty was a predictor for adverse health-related outcomes, including ADL disability and death.
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http://dx.doi.org/10.21149/spm.v57s1.7591 | DOI Listing |
Gac Med Mex
November 2024
Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Background: Older adults have highly heterogeneous aging rates.
Objective: To explore the association of biological age (BA) and accelerated aging with frailty in community-dwelling older adults.
Methods: We assessed 735 community-dwelling older adults from the Coyocan Cohort.
Background Racial and ethnic and sex differences in sleep may exist, but there are limited data directly comparing objective estimates of sleep-disordered breathing (SDB), particularly in rapid eye movement (REM) versus non-rapid eye movement (NREM) sleep, among Black, Mexican American (MA) and non-Hispanic White (NHW) men and women. Our goal is to investigate health disparities in SDB in a new, diverse cohort of older adults. Research Question Do SDB parameters during REM and NREM sleep differ by race and ethnicity or sex in community-dwelling older adults?.
View Article and Find Full Text PDFJ Nutr Health Aging
November 2024
Pediatric Obesity Clinic and Wellness Unit, Hospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico. Electronic address:
Objectives: Aging involves significant changes in body composition, marked by declines in muscle mass and bone mineral density alongside an increase in fat mass. Sarcopenia is characterized by low strength and muscle mass, and osteosarcopenia is the coexistence of sarcopenia and osteopenia/osteoporosis. Physiologically, there is a crosstalk between muscle and bone tissues mediated by several pathways.
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