Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499095 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Quantitative evaluation of China's public health emergencies response policies: a PMC index model approach.
BMC Public Health
January 2025
Shandong Second Medical University, Weifang, China.
Background: In recent years, public health emergencies, such as the COVID-19 pandemic and Ebola outbreaks, have occurred with increasing frequency worldwide, posing significant threats to global public health security. Policies serve as the foundation and institutional framework for effective emergency responses. Consequently, evaluating and optimizing the formulation and implementation of Public Health Emergency Response Policies (PHERPs) to enhance emergency response capacities has become an urgent and important research priority.
View Article and Find Full Text PDFArtificial neural network-driven modeling of Ebola transmission dynamics with delays and disability outcomes.
Comput Biol Chem
January 2025
Department of Mathematics, College of Science, Qassim University, Buraydah 51452, Saudi Arabia.
This study develops an Artificial Neural Network (ANN)-based framework to model the transmission dynamics and long-term disability outcomes of Ebola Virus Disease (EVD). Building on existing deterministic SEIR models, we extend the framework by introducing a disability compartment, capturing the progression of Ebola survivors to chronic health complications, such as post-Ebola syndrome. The proposed model stratifies the population into various epidemiological states, incorporating delays to better reflect the natural progression and intervention strategies associated with EVD.
View Article and Find Full Text PDFDecoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning.
Cell Host Microbe
January 2025
Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. Electronic address:
Evidence suggests that bats are important hosts of filoviruses, yet the specific species involved remain largely unidentified. Niemann-Pick C1 (NPC1) is an essential entry receptor, with amino acid variations influencing viral susceptibility and species-specific tropism. Herein, we conducted combinatorial binding studies with seven filovirus glycoproteins (GPs) and NPC1 orthologs from 81 bat species.
View Article and Find Full Text PDFInterventions to Maintain HIV/AIDS, Tuberculosis, and Malaria Service Delivery During Public Health Emergencies in Low- and Middle-Income Countries: Protocol for a Systematic Review.
JMIR Res Protoc
January 2025
Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Background: Although existing disease preparedness and response frameworks provide guidance about strengthening emergency response capacity, little attention is paid to health service continuity during emergency responses. During the 2014 Ebola outbreak, there were 11,325 reported deaths due to the Ebola virus and yet disruption in access to care caused more than 10,000 additional deaths due to measles, HIV/AIDS, tuberculosis, and malaria. Low- and middle-income countries account for the largest disease burden due to HIV, tuberculosis, and malaria and yet previous responses to health emergencies showed that HIV, tuberculosis, and malaria service delivery can be significantly disrupted.
View Article and Find Full Text PDFVaccination Strategies for Ebola in the Democratic Republic of Congo: The WHO-Ebola Modeling Collaboration.
Int J Infect Dis
January 2025
Department of Biostatistics, University of Florida, Gainesville, USA. Electronic address:
Objectives: Assess the effectiveness of ring vaccination in controlling an Ebola virus outbreak in the Democratic Republic of Congo.
Methods: This analysis focuses on two areas of the Democratic Republic of Congo, Beni and Butembo/Katwa, which were affected during the 2018-2020 Ebola outbreak. To simulate Ebola virus transmission, we used a spatially explicit agent-based model with households, health care facilities, and Ebola treatment units.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!