Lingual involvement can occur in a variety of neurological disorders including pyramidal, extrapyramidal and lower motor neuron disorders. It can be seen in the form of tremor, bradykinesia, dystonia, atrophy and weakness of tongue movements and can clinically present as difficulty in swallowing and dysarthria which can be a source of great discomfort to the patient. We describe a patient who presented with isolated lingual involvement and was diagnosed to have Wilsons's disease. This case emphasizes the clinical variability in presentation of Wilson's disease and importance of early clinical diagnosis.
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http://dx.doi.org/10.4103/0976-3147.154578 | DOI Listing |
Alzheimers Dement
December 2024
Memory & Aging Center, Department of Neurology, University of California in San Francisco, San Francisco, CA, USA.
Background: Frontotemporal lobar degeneration (FTLD)- TAR DNA-binding protein 43 (TDP) type C is commonly associated with a clinical diagnosis of semantic dementia (SD). Although anterior temporal lobe (ATL) is one of the primary atrophy centers, it is yet to be defined which other areas are involved in the TDP-type C pathology early in the disease course.
Methods: We included 16 patients with autopsy-confirmed FTLD-TDP type C from the database of the UCSF Memory and Aging Center: 13 patients with semantic variant primary progressive aphasia (svPPA) and predominant left ATL atrophy, and 3 patients with semantic behavioral variant frontotemporal dementia (sbvFTD) and predominant right ATL atrophy.
Front Neurosci
December 2024
Laboratory of Human Higher Nervous Activity, Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow, Russia.
Introduction: Time perception is a fundamental cognitive function, the brain mechanisms of which are not fully understood. Recent electroencephalography (EEG) studies have shown that neural oscillations in specific frequency bands may play a role in this process. In the current study, we sought to investigate how neurophysiological activity of cortical structures relates to subjective time estimations.
View Article and Find Full Text PDFJ Oral Rehabil
January 2025
Departamento de Fisioterapia, Centro Superior de Estudios Universitarios La Salle, Universidad Autónoma de Madrid, Madrid, Spain.
Background: There is a physiological association of the neck movements and jaw and tongue movements. However, there are no previous data regarding the performance of the tongue when the neck is under a lack of movement condition.
Objective: To quantify the tongue's maximal strength and mobility under an experimental restriction of cervical mobility.
Eur Respir J
January 2025
Department of Bacteriology and Immunology, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China
Background: Tuberculosis (TB) remains a major cause of infectious disease mortality globally, with significant underdiagnosis perpetuating transmission. Tongue swab analysis has emerged as a promising non-invasive method for pulmonary TB diagnosis. This study evaluates the diagnostic accuracy of the TB-EASY quantitative PCR (qPCR) assay using tongue swab specimens.
View Article and Find Full Text PDFImaging Sci Dent
December 2024
Division of Oral and Maxillofacial Radiology, Faculty of Dentistry, University of British Columbia, Vancouver, Canada.
Purpose: This study aimed to evaluate the quality of clinically indicated digital dental panoramic radiographs (DPRs) of children with mixed dentition. Despite the likely widespread use of this modality, recent research detailing errors on DPRs is scarce.
Materials And Methods: A consecutive case series was performed, including 178 DPRs from patients aged 6 to 12 years.
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