Human dirofilariasis is a zoonotic infection caused by worms of the genus Dirofilaria. Most reported cases involve Dirofilaria repens, and D. immitis infection has been rarely reported. Canines act as a reservoir for the infection, while human infections are sporadic. Human dirofilariasis has been widely reported in South Europe; however, the worldwide distribution constantly changes. We herein report an extremely rare case of subcutaneous trunk dirofilariasis in a 45-year-old immunosuppressed woman, caused by D. immitis. The parasitic infection was detected using ultrasonography. The infection was confirmed by a polymerase chain reaction-based method and was attributed to D. immitis.
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http://dx.doi.org/10.1016/j.jiph.2015.06.005 | DOI Listing |
Parasit Vectors
November 2024
Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Savska cesta 143, 10000, Zagreb, Croatia.
Pathogens
October 2024
Division of Parasitology and Parasitic Diseases, Department of Preclinical Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-786 Warsaw, Poland.
The nematode is responsible for a vector-borne disease affecting canines and humans worldwide, known as cardiopulmonary dirofilariasis. An accurate and early diagnosis is of the utmost importance for effective disease management. While traditional microscopy-based methods remain invaluable, they have inherent limitations.
View Article and Find Full Text PDFJ Nat Prod
December 2024
Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland 4072, Australia.
A chemical investigation of the Australian pasture soil-derived sp. S4S-00245B09, supported by chemical, bioactivity and cultivation profiling, yielded a new class of terpenyl-quinolin-4(1)-ones, goondolinones A and B ( and ), featuring an unprecedented fused seven-membered ether. Structures were assigned to and on the basis of detailed spectroscopic analysis, including X-ray analysis of , and biosynthetic considerations.
View Article and Find Full Text PDFParasit Vectors
November 2024
Department of Veterinary Clinical Sciences, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Background: Dirofilaria sp. "hongkongensis" is a putative Dirofilaria species, initially identified in subcutaneous nodules in humans in Hong Kong and in other South and Southeast Asian regions. While it differs genetically from the better-known zoonotic species, Dirofilaria repens and Dirofilaria immitis, information on the lesions caused by Dirofilaria sp.
View Article and Find Full Text PDFPLoS Negl Trop Dis
November 2024
Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Introduction: Filarial pathogens are described to inhabit and affect subcutaneous and lymphatic tissues of the human host. To date, little is known on how much oral health might be affected by filarial infections, even though involvement of the oro-facial region is pathophysiologically possible. Therefore, we conducted this systematic review of the literature to help reduce the current evidence gap.
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