Conductive hearing loss with an intact tympanic membrane due to non-inflammatory causes.

Auris Nasus Larynx

Department of Otolaryngology-Head and Neck Surgery, Kyungpook National University College of Medicine, Daegu, Republic of Korea. Electronic address:

Published: April 2016

Objective: We analyzed audiologic and surgical findings in patients with conductive hearing loss (CHL) with an intact tympanic membrane (TM) that was of a non-inflammatory origin.

Methods: We reviewed data from patients who underwent exploratory tympanotomy for CHL with intact TM from January 1995 to November 2012. Patients with diseases of non-inflammatory origin were enrolled (69 patients; 79 ears). Patients were categorized into two groups: non-trauma (50 ears) and trauma (29 ears). Demographic data, intraoperative findings, and audiologic results were obtained and analyzed.

Results: Overall, the second decade was the most common age of diagnosis in both the non-trauma and trauma groups. Operative findings showed that ossicular dislocation was more prevalent than ossicular fixation; all trauma group subjects had ossicular dislocation. Short columellization or partial ossicular replacement was the most frequently adopted surgical procedures in both groups. Overall, audiologically, air-conduction thresholds (ACs) and air-bone gaps were significantly improved over the short- and long-term period in both groups. However, the non-trauma group had significantly higher preoperative ACs than the trauma group, especially at low frequencies.

Conclusion: This study provides clinicians with useful information regarding the clinical characteristics of CHL with intact TM of non-inflammatory origin.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anl.2015.06.004DOI Listing

Publication Analysis

Top Keywords

chl intact
12
conductive hearing
8
hearing loss
8
intact tympanic
8
tympanic membrane
8
membrane non-inflammatory
8
non-inflammatory origin
8
groups non-trauma
8
ossicular dislocation
8
trauma group
8

Similar Publications

Nodular lymphocyte predominant Hodgkin lymphoma was termed "nodular lymphocyte predominant B-cell lymphoma" in the International Consensus Classification (ICC), to emphasize clinical and biological differences from classic Hodgkin lymphoma (CHL). The abbreviation "NLP" represents both terms in the ICC and World Health Organization classifications. Variations in the growth pattern, originally reported as Fan patterns A-F, are designated as either grade 1 or grade 2 in the ICC.

View Article and Find Full Text PDF

Cardiotoxicity of the diamide insecticide chlorantraniliprole in the intact heart and in isolated cardiomyocytes from the honey bee.

Sci Rep

June 2024

Institut National de la Recherche pour l'Agriculture, l'Alimentation et l'Environnement, INRAE, UR406 Abeilles et Environnement, Avignon, France.

In honey bees, circulation of blood (hemolymph) is driven by the peristaltic contraction of the heart vessel located in the dorsal part of the abdomen. Chlorantraniliprole (CHL) is an insecticide of the anthranilic diamide class which main mode of action is to alter the function of intracellular Ca release channels (known as RyRs, for ryanodine receptors). In the honey bee, it was recently found to be more toxic when applied on the dorsal part of the abdomen, suggesting a direct cardiotoxicity.

View Article and Find Full Text PDF

Ultrafast energy quenching mechanism of LHCSR3-dependent photoprotection in Chlamydomonas.

Nat Commun

May 2024

Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.

Photosynthetic organisms have evolved an essential energy-dependent quenching (qE) mechanism to avoid any lethal damages caused by high light. While the triggering mechanism of qE has been well addressed, candidates for quenchers are often debated. This lack of understanding is because of the tremendous difficulty in measuring intact cells using transient absorption techniques.

View Article and Find Full Text PDF

Evaluation of Conventional MR Imaging of the Shoulder in the Diagnosis of Lesions of the Biceps Pulley.

Acad Radiol

August 2024

Department of Radiology, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Ismaninger Strasse 22, 81675 Munich, Germany; Musculoskeletal Radiology Section, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Ismaninger Strasse 22, 81675 Munich, Germany.

Article Synopsis
  • The study aimed to evaluate the effectiveness and consistency of conventional MRI in diagnosing biceps pulley lesions, using arthroscopy for comparison.* -
  • Analyzing MRI results from 68 patients, the researchers found that MRI had high sensitivity (around 95%) and moderate specificity (about 61-80%) for identifying pulley lesions, with good agreement among radiologists.* -
  • The most reliable indicators included biceps tendinopathy and defects in specific ligaments, while subluxation/dislocation of the tendon was less reliable in sensitive detection but more specific.*
View Article and Find Full Text PDF

Unlabelled: Chlorophyll is synthesized from chlorophyllide , catalyzed by chlorophyllide oxygenase (). To examine whether reduced chlorophyll content regulates chlorophyll (Chl) synthesis and photosynthesis, we raised transgenic tobacco plants with antisense expression, which had lower chlorophyll content and, thus, higher Chl / ratio. Further, these plants had (i) lower chlorophyll and total Chl content, whether they were grown under low or high light; (ii) decreased steady-state levels of chlorophyll biosynthetic intermediates, due, perhaps, to a feedback-controlled reduction in enzyme expressions/activities; (iii) reduced electron transport rates in their intact leaves, and reduced Photosystem (PS) I, PS II and whole chain electron transport activities in their isolated thylakoids; (iv) decreased carbon assimilation in plants grown under low or high light.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!