Two unusual cases of intravascular fasciitis arising in a 25-year-old female and a 26-year-old male are presented here. The lesions apparently presented as firm, raised, submucosal nodules on the tongue. Intravascular fasciitis (IVF) shares the microscopic features of nodular fasciitis (NF), but with intraluminal, intramural, and extramural involvement of small- to medium-sized veins and arteries with a multinodular or serpentine growth pattern along the course of affected blood vessels. NF is a benign lesion occurring on the trunk and upper extremities with a strong predilection for young adults 20 to 40 years of age. Intraoral NF is uncommon, and intraoral IVF is extremely rare, with only sporadic reports in the literature. In both of our cases, the patient's main concern was rapid growth of the lesion, which was nontender, on the tongue. The clinical, histologic, and immunohistochemical features and treatment are presented, along with a review of the literature.
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Article Synopsis
- Intravascular fasciitis (IF) is a rare but benign condition that occurs in the fascia surrounding small to medium blood vessels.
- An 8-year-old boy with swelling in the groin was found to have a deep vein thrombosis but later developed an unusual mass, leading to the discontinuation of treatment with anticoagulants.
- After surgery and examination, the mass was identified as intravascular fasciitis, highlighting the need for doctors to differentiate IF from more serious conditions like sarcoma and thrombosis.
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