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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495134 | PMC |
| http://dx.doi.org/10.5114/pwki.2015.52291 | DOI Listing |
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Bilateral femoral neck fractures and fixation failure due to stiff-person syndrome.
Pract Neurol
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Neurology Department, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
We describe a woman with stiff-person syndrome (SPS), whose muscle spasms resulted in sequential bilateral femoral neck fractures. Orthopaedic fixation of the first fracture was complicated by increased muscle spasm, fracture nonunion and ultimately metalwork fracture. SPS was diagnosed following the fracture of the contralateral femoral neck, neurology assessment and detection of high-titre antibodies to glutamic acid decarboxylase.
View Article and Find Full Text PDFDose-related effect of acetylcholine on human gingival blood flow.
BMC Oral Health
November 2024
Department of Restorative Dentistry and Endodontics, Faculty of Dentistry, Semmelweis University, H-1088 Budapest, Szentkirályi utca 47, Budapest, Hungary.
Background: This study investigates the dose-response relationship of acetylcholine (ACh) on healthy human gingival blood flow (GBF). Understanding this dose-response relationship contributes to studying vasodilatory mechanisms in various pathological conditions.
Methods: The study involved 22 young healthy men (21 - 32 years) to investigate the dose-response relationship of ACh on GBF.
Five weeks of intermittent hand exposures to alternating cold and hot stimuli do not modify finger cold-induced vasodilatation response.
J Therm Biol
October 2024
Division of Environmental Physiology, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden; Division of Environmental Physiology, Swedish Aerospace Physiology Center, KTH Royal Institute of Technology, Stockholm, Sweden. Electronic address:
We tested the hypothesis that prolonged intermittent hand exposures to transient contrast thermal stimuli would enhance the finger cold-induced vasodilatation (CIVD) response during localized cooling. Eight healthy men participated in a 5-week regimen, during which they immersed, thrice per week, the non-dominant (EXP) hand in 8° and 43 °C water, sequentially and at 3-min intervals, for a total period of 60 min. The contralateral (i.
View Article and Find Full Text PDFCharacterization of a rapid avoidance behavior in Manduca sexta larvae in response to noxious stimuli.
J Exp Biol
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Department of Biology, Tufts University, 200 Boston Ave, Medford, MA 02155, USA.
This study focuses on the nociceptive responses observed in the tobacco hornworm (Manduca sexta). While prior investigations have described the sensory neurons and muscle activation patterns associated with the 'strike' behavior, there remains a gap in our understanding of the alternative 'withdrawal' movement, wherein the animal bends its head and thorax away from the stimulus. Our results show that stimulus location determines which nocifensive behavior is elicited.
View Article and Find Full Text PDFArticle Synopsis
- - Recent research on visual working memory (VWM) shows there’s a hierarchy of memory storage, where less relevant memories can shift to a passive state, allowing current memories to be actively manipulated.
- - Stimulating this passive memory can reactivate it, potentially causing interference with active memory; hence, to maintain stability, passive memory may require suppression during active tasks.
- - Experiments measuring brain activity while participants performed memory tasks indicated that while passive memories are maintained, there is a neural suppression of these memories that remains unaffected by the load of active memory tasks.
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