A draft genome sequence of Streptomyces incarnatus NRRL8089, which produces the nucleoside antibiotic sinefungin, is described here. The genome contains 8,897,465 bp in 76 contigs and 8,266 predicted genes. Interestingly, the genome encodes an open reading frame for selenocysteine-containing formate dehydrogenase-O and the selenoprotein biosynthetic gene cluster selABCD.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498112PMC
http://dx.doi.org/10.1128/genomeA.00715-15DOI Listing

Publication Analysis

Top Keywords

draft genome
8
genome sequence
8
sequence streptomyces
8
streptomyces incarnatus
8
incarnatus nrrl8089
8
nrrl8089 produces
8
produces nucleoside
8
nucleoside antibiotic
8
antibiotic sinefungin
8
sinefungin draft
4

Similar Publications

Sixty-five draft genome sequences of and from table egg layer chickens.

Microbiol Resour Announc

January 2025

Egg and Poultry Production Safety Research Unit, USDA Agricultural Research Service, Athens, Georgia, USA.

We present the draft genomic sequences of 65 isolates of spp. (38 and 27 ) isolated from table egg-layer chickens, which are not generally associated with human transmission. Up to this time, there are no publicly available genomic sequences of isolated from laying hens.

View Article and Find Full Text PDF

Draft genome sequence of sp. SA01 isolated from seedlings collected in Cape Cod (USA).

Microbiol Resour Announc

January 2025

The Ecosystems Center, Marine Biological Laboratory, Woods Hole, Massachusetts, USA.

A draft genome was generated for a strain of closely related to sp. ENV421 isolated from plants of smooth cordgrass germinated from seeds collected in a salt marsh in Cape Cod (USA). Genomic DNA was sequenced using paired-end Illumina technologies.

View Article and Find Full Text PDF

The Ralstonia solanacearum Species Complex (RSSC) is the most significant plant pathogen group with a wide host range. It is genetically related but displays distinct biological features, such as restrictive geography occurrence. The RSSC comprises three species: Ralstonia pseudosolanacearum (phylotype I and III), Ralstonia solanacearum (phylotype IIA and IIB), and Ralstonia syzygii (phylotype IV) (Fegan and Prior 2005).

View Article and Find Full Text PDF

Lorchels, also known as false morels (Gyromitra sensu lato), are iconic due to their brain-shaped mushrooms and production of gyromitrin, a deadly mycotoxin. Molecular phylogenetic studies have hitherto failed to resolve deep-branching relationships in the lorchel family, Discinaceae, hampering our ability to settle longstanding taxonomic debates and to reconstruct the evolution of toxin production. We generated 75 draft genomes from cultures and ascomata (some collected as early as 1960), conducted phylogenomic analyses using 1542 single-copy orthologs to infer the early evolutionary history of lorchels, and identified genomic signatures of trophic mode and mating-type loci to better understand lorchel ecology and reproductive biology.

View Article and Find Full Text PDF

Background: Plasma phospho-tau biomarkers, such as p217+tau, excel at identifying Alzheimer's Disease (AD) neuropathology. However, questions remain regarding their capacity to inform AD biological PET stages at group level and maintain the same precision at individual patient level.

Method: Participants included 248 cognitively unimpaired (CU) and 227 cognitively impaired (CI) individuals, with Janssen plasma p217+tau Simoa® assay, F-NAV4694 Aβ PET (A) and F-MK6240 tau PET (T) data.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!