AI Article Synopsis
- * A severe case was reported involving a 33-year-old man who developed Stevens-Johnson syndrome and suffered hepatic failure after taking lamotrigine for two weeks.
- * This highlights the need for monitoring liver function in patients taking lamotrigine due to the risk of serious complications, including potential fatality.
Article Abstract
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs. However, a 33-year-old male patient who was admitted with Stevens-Johnson syndrome after taking lamotrigine for 15 days experienced hepatic failure and died 5 days after admission. This case demonstrates the importance of realizing that lamotrigine can lead to fatal hepatic failure, and that tests for the normal liver function should be performed when administering lamotrigine.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493362 | PMC |
| http://dx.doi.org/10.3350/cmh.2015.21.2.180 | DOI Listing |
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