We have developed a novel approach in cancer immunotherapy, the personalized peptide vaccination (PPV), in which human leukocyte antigen (HLA)-matched peptides are selected on the basis of preexisting host immunity before vaccination. Recently, we demonstrated the feasibility of PPV in previously treated patients with advanced colorectal cancer, thus warranting further clinical development of this approach.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485709 | PMC |
| http://dx.doi.org/10.1080/2162402X.2015.1005512 | DOI Listing |
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