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| http://dx.doi.org/10.3238/arztebl.2015.0374b | DOI Listing |
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Metastasis lesion segmentation from bone scintigrams using encoder-decoder architecture model with multi-attention and multi-scale learning.
Quant Imaging Med Surg
January 2025
School of Computing, Mathematics and Engineering, Charles Sturt University, Albury, Australia.
Background: The limitation in spatial resolution of bone scintigraphy, combined with the vast variations in size, location, and intensity of bone metastasis (BM) lesions, poses challenges for accurate diagnosis by human experts. Deep learning-based analysis has emerged as a preferred approach for automating the identification and delineation of BM lesions. This study aims to develop a deep learning-based approach to automatically segment bone scintigrams for improving diagnostic accuracy.
View Article and Find Full Text PDF[Biomarkers in complex regional pain syndrome].
Schmerz
January 2025
Klinik für Anästhesiologie, Intensivmedizin, Notfallmedizin und Schmerztherapie, Zentrum für interdisziplinäre Schmerzmedizin (ZiS), Universitätsklinikum Würzburg, Oberdürrbacher Straße 6, 97080, Würzburg, Deutschland.
Complex regional pain syndrome (CRPS) is a severe pain disorder with an unclear pathophysiology. Biomarkers offer opportunities to enhance diagnosis, stratification, prognosis, and monitoring. Serum markers such as cytokines and microRNAs show potential but require further research.
View Article and Find Full Text PDFUncovering Hidden Metastases at Unusual Site: Emphasizing the Role of 177Lu-PSMA Posttherapy Scan in Detecting Rare Foot Metastasis in mCRPC.
Clin Nucl Med
February 2025
From the Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Prostate cancer frequently metastasizes to bones; however, the detection of metastases can be challenging in rare locations. We present the case of a 76-year-old man with metastatic castration-resistant prostate cancer with lymph nodal and skeletal metastases who underwent 177Lu-prostate-specific membrane antigen (PSMA) therapy. Initial 18F-PSMA PET/CT scan acquired until the midthigh failed to identify metastases in the foot, but posttherapy 177Lu-PSMA scan revealed the presence of metastases in the navicular and cuboid bones of the right foot, which is a very rare finding.
View Article and Find Full Text PDFDisseminated Extranodal Natural Killer/T-Cell Lymphoma Mimicking a Paraneoplastic Polymyositis.
Clin Nucl Med
February 2025
From the Department of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai West, New York, NY.
Extranodal natural killer/T-cell lymphoma (ENKTCL) is an aggressive EBV-associated non-Hodgkin lymphoma, most commonly arising from within the mucosa of the upper aerodigestive tract, typically with nasal presentation. Here, we present an interesting case of a 36-year-old man with ENKTCL with an atypical pattern of disease progression despite 3 cycles of SMILE chemotherapy. Restaging 18F-FDG PET/CT demonstrated widespread uptake within the skeletal musculature in a distribution concerning for a paraneoplastic polymyositis.
View Article and Find Full Text PDFA modified orthogonal-distance ray-tracer method applied to dual rotation PET systems.
Phys Med Biol
January 2025
University of Aveiro, Physics Department Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
a new projector, orthogonal-distance ray-tracer varying-full width at half maximum (OD-RT-VF), was developed to model a shift-variant elliptical point-spread function (PSF) response to improve the image quality (IQ) of a preclinical dual-rotation PET system.the OD-RT-VF projector models different FWHM values of the PSF in multiple directions, using half-height and half-width tube-of-response (ToR) values. The OD-RT-VF method's performance was evaluated against the original OD-RT method and a ToR model with constant response.
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