Background: Skin problems in the elderly population have rarely been the subject of scientific research.
Objectives: The present study aimed to determine the prevalences of the most common dermatological conditions in elderly subjects and to investigate their associations with systemic diseases.
Methods: The study involved a group of 198 consecutive patients aged ≥ 65 years who were admitted to the Departments of Dermatology and Geriatrics at the study institution. All participants were thoroughly evaluated in a clinical interview and physical examination in which special emphasis was placed on dermatological issues.
Results: All subjects presented at least one dermatological condition. A significant correlation was found between the number of systemic diseases and the number of different skin lesions observed. The most common skin disorders included solar lentigines, senile angiomas, xerosis, seborrheic warts, varicose veins, edema of the lower legs, and pruritus. Patients aged ≥ 75 years demonstrated solar lentigines, edema of the lower legs, clavi, solar keratoses, and onychomycosis significantly more often, whereas patients aged < 75 years suffered more frequently from psoriasis. Diabetes was associated with the development of onychomycosis; hypercholesterolemia promoted the incidence of xanthomas and drug-induced skin reactions; chronic obstructive pulmonary disease was associated with senile purpura; and hypothyroidism favored the occurrence of varicose veins in the lower legs and telogen effluvium.
Conclusions: Skin disorders are common in elderly people. Systemic diseases promote the development of dermatological conditions. A comprehensive approach to health problems in elderly subjects requires knowledge of dermatology.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/ijd.12832 | DOI Listing |
Exp Dermatol
January 2025
Department of Dermatology, Kansai Medical University, Hirakata, Osaka, Japan.
Chronic inflammation in the tumour microenvironment (TME) via Th2-polarisation promotes melanoma progression and metastasis, making it a target for immunotherapy. Interleukin (IL)-4 is considered essential for Th2-polarisation in the TME; however, its source remains unknown. Basophils have been postulated as one of its sources.
View Article and Find Full Text PDFCancer
February 2025
General Medicine Service, VA Puget Sound Health Care System, Seattle, Washington, USA.
Background: Breast cancer screening (BCS) inequities are evident at national and local levels, and many health systems want to address these inequities, but may lack data about contributing factors. The objective of this study was to inform health system interventions through an exploratory analysis of potential multilevel contributors to BCS inequities using health system data.
Methods: The authors conducted a cross-sectional analysis within a large academic health system including 19,774 individuals who identified as Black (n = 1445) or White (n = 18,329) race and were eligible for BCS.
J Ren Care
March 2025
NephroCare Italia, Napoli, Italy.
Background: Uremic pruritus is a quite common condition among patients with chronic kidney disease. Symptom severity and patterns are variable.
Aim: To assess how nurses in the field of nephrology perceive the issue of uremic pruritus in dialysis patients and the relevance of this condition.
Cancer Med
February 2025
Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
Introduction: Immune checkpoint inhibitors (ICI) have improved the therapeutic arsenal in outpatient oncology care; however, data on necessity of hospitalizations associated with immune-related adverse events (irAEs) are scarce. Here, we characterized hospitalizations of patients undergoing ICI, from the prospective cohort study of the immune cooperative oncology group (ICOG) Hannover.
Methods: Between 12/2019 and 06/2022, 237 patients were included.
Stat Med
February 2025
Department of Mathematical Sciences, University of Texas at Dallas, Richardson, Texas, USA.
Multi-gene panel testing allows efficient detection of pathogenic variants in cancer susceptibility genes including moderate-risk genes such as ATM and PALB2. A growing number of studies examine the risk of breast cancer (BC) conferred by pathogenic variants of these genes. A meta-analysis combining the reported risk estimates can provide an overall estimate of age-specific risk of developing BC, that is, penetrance for a gene.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!