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http://dx.doi.org/10.3109/09638288.2015.1062924 | DOI Listing |
Sci Rep
January 2025
Laboratory for Critical Care Physiology, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, USA.
Mitochondrial transplantation (MTx) offers a promising therapeutic approach to mitigate mitochondrial dysfunction in conditions such as ischemia-reperfusion (IR) injury. The quality and viability of donor mitochondria are critical to MTx success, necessitating the optimization of isolation protocols. This study aimed to assess a rapid mitochondrial isolation method, examine the relationship between mitochondrial size and membrane potential, and evaluate the potential benefits of Poloxamer 188 (P-188) in improving mitochondrial quality during the isolation process.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2025
Department of Physiology and Membrane Biology, University of California Davis, Davis, CA 95616.
The L-type Ca channel (Ca1.2) is essential for cardiac excitation-contraction coupling. To contribute to the inward Ca flux that drives Ca-induced-Ca-release, Ca1.
View Article and Find Full Text PDFActa Bioeng Biomech
September 2024
Institute of Advanced Research for Sport and Health Science, Ritsumeikan University, Japan.
: Toe flexor strength (TFS) has been determined to evaluate the toe flexor muscle function. However, it is unclear how strength and size relationships of toe flexor muscles vary depending on the toes intended for force production. We aimed to clarify this by examining the relationship between TFS and toe flexor muscle size, and hypothesized TFS produced by all toes (TFS-All), the great toe (TFS-Great) and lesser toes (TFS-Lesser) would be specifically associated with the size of the muscles specialized in each corresponding toe flexion.
View Article and Find Full Text PDFPurpose: This study defines correlative and causal relationships between muscle strength and size before and after unilateral resistance training (RT) in a large cohort of healthy adults, focusing on sex differences within these relationships.
Methods: Results from 1233 participants (504 males and 729 females) in a retrospective analysis were included. Maximal voluntary isometric contraction strength (MVC), one-repetition maximum strength (1RM), biceps cross-sectional area (CSA) and elbow flexor volume (VOL) measures of the non-dominant and dominant arm were evaluated from baseline and after 12-wk RT twice per week.
Front Neurol
January 2025
Department of Rehabilitation, Maruki Memorial Medical and Social Welfare Center, Saitama, Japan.
Background: Evidence of the effectiveness of physiotherapy, including muscle strength training, coordination training, aerobic exercise, cycling regimen, balance training, gait training, and activity of daily living training, in patients with degenerative cerebellar ataxia (DCA) was insufficient for clinical decision making. We aimed to explore clinical outcomes and examine the parameters associated with physical impairment and activity in people with DCA based on preregistration (PROSPERO: CRD42024493883).
Methods: The PubMed, Cochrane Library, CHINAL, and PEDro databases were searched for relevant randomized controlled trials (RCTs).
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