Submerged culture of the pyrenomycete Melanconis flavovirens produces a strongly active antifungal antibiotic. The antibiotic was isolated from the culture mash. In purified compound the physico-chemical characteristics, including 1H NMR spectrum, were estimated. The antibiotic was found to be identical with thermozymocidin (myriocin) as confirmed by comparison with synthetically prepared thermozymocidin.

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http://dx.doi.org/10.1002/jobm.3620290619DOI Listing

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