Acute coronary syndrome (ACS) still remains one of the leading causes of mortality and morbidity worldwide. Seven to fifteen percent of patients presenting with ACS have unobstructed coronary artery disease (CAD) on urgent angiography. Patients with ACS and unobstructed coronary arteries represent a clinical dilemma and their diagnosis and management is quite variable in current practice. Cardiovascular magnetic resonance imaging with its unique non-invasive myocardial tissue characterization property has the potential to identify underlying etiologies and reach a final diagnosis. These include acute and chronic myocarditis, embolic/spontaneous recanalization myocardial infarction, and Tako-Tsubo cardiomyopathy, and other conditions. Establishing a final diagnosis has a direct implication on patient's management and prognosis. In this article, we have reviewed the current evidence on the diagnostic role of cardiac magnetic resonance (CMR) in patients with ACS and unobstructed coronary arteries. We have also highlighted the potential role of CMR as a risk stratification or prognostication tool for this patient population.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483181 | PMC |
http://dx.doi.org/10.1007/s12410-015-9345-x | DOI Listing |
Cureus
November 2024
Internal Medicine, Frimley Health Foundation Trust, Slough, GBR.
Takotsubo cardiomyopathy (TCM) is characterized by transient left ventricular dysfunction in the absence of significant coronary artery disease. First described in Japan in the 1990s by Sato et al., this unique reversible cardiomyopathy typically occurs in post-menopausal women and is frequently triggered by physical or physiological stress.
View Article and Find Full Text PDFEur Cardiol
November 2024
Department of Cardiology and Angiology, Robert Bosch Hospital Stuttgart, Germany.
Eur Heart J Case Rep
November 2024
Department of Cardiology, Glenfield Hospital, University Hospitals of Leicester, Leicester LE3 9QP, UK.
Eur Heart J Case Rep
August 2024
Department of Cardiology and Angiology, Robert-Bosch-Krankenhaus, Auerbachstr. 110, Stuttgart 70376, Germany.
Background: Approximately 5-15% of patients with acute coronary syndrome have myocardial infarction with unobstructed coronary arteries (MINOCA). Guidelines recommend invasive assessments to identify underlying causes for MINOCA such as coronary artery spasm (CAS), spontaneous coronary dissection, or microvascular disease as well as non-invasive assessments in search of myocarditis, takotsubo syndrome, or cardiomyopathies.
Case Summary: A 54-year-old male patient presented with ST-segment elevation myocardial infarction (STEMI).
J Am Heart Assoc
July 2024
INSERM UMR_S 999 Pulmonary Hypertension: Pathophysiology and Novel Therapies Le Plessis Robinson France.
Background: The primary genetic risk factor for heritable pulmonary arterial hypertension is the presence of monoallelic mutations in the gene. The incomplete penetrance of mutations implies that additional triggers are necessary for pulmonary arterial hypertension occurrence. Pulmonary artery stenosis directly raises pulmonary artery pressure, and the redirection of blood flow to unobstructed arteries leads to endothelial dysfunction and vascular remodeling.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!