We report a novel sensing method for fluorescence-labelled microRNAs (miRNAs) spotted on an all-dielectric photonic structure. Such a photonic structure provides an enhanced excitation and a directional beaming of the emitted fluorescence, resulting in a significant improvement of the overall signal collected. As a result, the Limit of Detection (LoD) is demonstrated to decrease by a factor of about 50. A compact read-out system allows a wide-field imaging-based detection, with little or no optical alignment issues, which makes this approach particularly interesting for further development for example in microarray-type bioassays.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c5an00889a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Reduction of Streak Artifacts in the Superior Vena Cava for Better Visualization of Mediastinal Structures Through Virtual Monoenergetic Reconstructions Using a Photon-counting Detector Computed Tomography.
J Thorac Imaging
January 2025
Department of Radiology and Nuclear Medicine, University Medical Centre Mannheim.
Purpose: Computed tomography (CT) is crucial in oncologic imaging for precise diagnosis and staging. Beam-hardening artifacts from contrast media in the superior vena cava can degrade image quality and obscure adjacent structures, complicating lymph node assessment. This study examines the use of virtual monoenergetic reconstruction with photon-counting detector CT (photon-counting CT) to mitigate these artifacts.
View Article and Find Full Text PDFRoom temperature ferroelectricity in monolayer graphene sandwiched between hexagonal boron nitride.
Nat Commun
January 2025
Key Laboratory for Intelligent Nano Materials and Devices of Ministry of Education, State Key Laboratory of Mechanics and Control of Mechanical Structures, and Institute for Frontier Science, Nanjing University of Aeronautics and Astronautics, Nanjing, China.
The ferroelectricity in stacked van der Waals multilayers through interlayer sliding holds great promise for ultrathin high-density memory devices, yet mostly subject to weak polarization and cryogenic operating condition. Here, we demonstrate robust room-temperature ferroelectricity in monolayer graphene sandwiched between hexagonal boron nitride layers with a rhombohedral-like stacking (i.e.
View Article and Find Full Text PDFTransformer-generated atomic embeddings to enhance prediction accuracy of crystal properties with machine learning.
Nat Commun
January 2025
School of Information Science and Technology, Fudan University, Shanghai, China.
Accelerating the discovery of novel crystal materials by machine learning is crucial for advancing various technologies from clean energy to information processing. The machine-learning models for prediction of materials properties require embedding atomic information, while traditional methods have limited effectiveness in enhancing prediction accuracy. Here, we proposed an atomic embedding strategy called universal atomic embeddings (UAEs) for their broad applicability as atomic fingerprints, and generated the UAE tensors based on the proposed CrystalTransformer model.
View Article and Find Full Text PDFMethylammonium-free, high-efficiency, and stable all-perovskite tandem solar cells enabled by multifunctional rubidium acetate.
Nat Commun
January 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, PR China.
All-perovskite tandem solar cells (APTSCs) offer the potential to surpass the Shockley-Queisser limit of single-junction solar cells at low cost. However, high-performance APTSCs contain unstable methylammonium (MA) cation in the tin-lead (Sn-Pb) narrow bandgap subcells. Currently, MA-free Sn-Pb perovskite solar cells (PSCs) show lower performance compared with their MA-containing counterparts.
View Article and Find Full Text PDFObservation of ultraviolet photothermoelectric bipolar impulse in gallium-based heterostructure nanowires.
Nat Commun
January 2025
Key Laboratory of Advanced Photonic and Electronic Materials, Key Laboratory of Optoelectronic Devices and Systems with Extreme Performances of MOE and School of Electronic Science and Engineering, Nanjing University, Nanjing, 210093, China.
The incorporation of thermal dynamics alongside conventional optoelectronic principles holds immense promise for advancing technology. Here, we introduce a GaON/GaN heterostructure-nanowire ultraviolet electrochemical cell of observing a photothermoelectric bipolar impulse characteristic. By leveraging the distinct thermoelectric properties of GaON/GaN, rapid generation of hot carriers establishes bidirectional instantaneous gradients in concentration and temperature within the nanoscale heterostructure via light on/off modulation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!