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Macrotrabecular-Massive Hepatocellular Carcinoma: A Case Report.
Cureus
December 2024
Department of Clinical Immunology and Allergology, Iuliu Hatieganu University of Medicine and Pharmacy of Cluj, Cluj-Napoca, ROU.
Macrotrabecular-massive hepatocellular carcinoma (MTM-HCC) is a rare and aggressive molecular subtype of hepatocellular carcinoma (HCC) associated with a poor prognosis. Unlike typical HCC, which commonly arises in the context of cirrhosis, MTM-HCC can develop in non-cirrhotic livers, presenting unique diagnostic and therapeutic challenges. This case report describes a 35-year-old male who presented with persistent epigastric pain, fatigue, and loss of appetite.
View Article and Find Full Text PDFAutosomal Dominant Polycystic Kidney Disease.
Adv Kidney Dis Health
November 2024
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN. Electronic address:
Article Synopsis
- Over 50% of individuals with autosomal dominant polycystic kidney disease (ADPKD) will experience kidney failure, making it the 4th leading cause of end-stage kidney disease.
- ADPKD is a systemic disorder impacting not just the kidneys, but also the liver, heart, and other organs, with some patients facing severe issues like liver enlargement or aneurysm ruptures.
- Recent advances in genetics, prognosis, and treatment strategies have enabled personalized care that can alter the disease's progression, with the review emphasizing diagnosis, kidney failure risk assessment, treatment options, blood pressure control, and genetic testing.
Transileocolic Portal Vein Embolization Increases Remnant Liver Volume After Major Hepatectomy.
In Vivo
October 2024
Department of Surgery, Matsuyama Red Cross Hospital, Matsuyama, Japan.
Background/aim: Transileocolic portal vein embolization (TIPE) may reduce the risk of liver failure after massive hepatectomy. However, convincing evidence of its usefulness in this regard is yet to be reported. Therefore, this study aimed to investigate the use of TIPE after massive hepatectomy.
View Article and Find Full Text PDFMassive Hepatomegaly in a Pediatric Patient Due to a Solitary Simple Hepatic Cyst: A Case Report.
Cureus
September 2024
College of Medicine, National University of Science and Technology, Muscat, OMN.
This case report presents a six-year-old male patient with massive hepatomegaly attributed to a solitary simple hepatic cyst. The patient was referred to the pediatric gastroenterology clinic after his family noted progressive abdominal distention over four months, with no associated symptoms such as pain, jaundice, or systemic illness. Physical examination revealed significant hepatomegaly and initial laboratory investigations indicated mild transaminitis but were otherwise unremarkable.
View Article and Find Full Text PDFScrub typhus presenting with massive splenomegaly and lobar pneumonia.
Natl Med J India
October 2024
General Medicine, Institute of Medical Sciences and SUM Hospital, Kalinga Nagar, Bhubaneswar 751003, Odisha, India.
Scrub typhus is still an underdiagnosed disease despite an increase in incidence as the clinical presentation is often different, leading to a low index of suspicion among doctors. Scrub typhus, an acute febrile disease, is a cause of prolonged fever and pyrexia of unknown origin. It can have varied clinical presentations ranging from mild asymptomatic disease to fatal multi-organ dysfunction.
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