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Technoeconomic analysis for near-term scale-up of bioprocesses.
Curr Opin Biotechnol
January 2025
Life-cycle, Economics, and Agronomy Division, Joint BioEnergy Institute, Emeryville, CA 94608, United States; Energy & Biosciences Institute, University of California, Berkeley, CA 94720, United States; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States; Energy Analysis and Environmental Impacts Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States. Electronic address:
Growing the bioeconomy requires products and pathways that are cost-competitive. Technoeconomic analyses (TEAs) aim to predict the long-term economic viability and often use what are known as n plant cost and performance parameters. However, as TEA is more widely adopted to inform everything from early-stage research to company and investor decision-making, the n plant approach is inadequate and risks being misused to inform the early stages of scale-up.
View Article and Find Full Text PDFRole playing in human evolution: from life to art, and everything in between.
Front Psychol
January 2025
Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada.
Role playing is a central, but underappreciated, process in human evolution. It is a feature not only of the theatrical arts, but of everyday social interactions. While some role playing is limited to enacting various personas of the self (e.
View Article and Find Full Text PDF"What Are Some of the Things You Are Worried About?": An Analysis of Youth's Open-Ended Responses of Current Worries.
J Adolesc
January 2025
Department of Psychology, Brock University, Ontario, Canada.
Introduction: There is widespread concern that contemporary global issues (e.g., climate change, technology use) are exacerbating a "youth wellbeing crisis.
View Article and Find Full Text PDFAdaptive clinical trial of AZD7442 and SARS-CoV-2 vaccination in immunosuppressed patients highly vulnerable to infection with SARS-CoV-2 virus (RAPID-PROTECTION): protocol for a multicentre, interventional open-label, randomised controlled trial.
BMJ Open
January 2025
Department of Oncology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Introduction: Despite repeated vaccinations against SARS-CoV-2 virus, patients who are immunocompromised remain at very high risk of catching SARS-CoV-2 virus and becoming unwell. AZD7442 (Evusheld) is a long-acting monoclonal antibody treatment that has been shown in clinical trials to prevent SARS-CoV-2 infection for up to a year after a single dose. Vaccines require a healthy immune system to generate protective immunity.
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