Pharmacologic inhibition of the mutant BRAF protein in advanced BRAF melanoma results in a high proportion of patients that respond, but few with durable responses. We have recently revealed that Natural Killer (NK) cells play an essential role in the inhibitor control of melanoma metastases in mice that may be therapeutically exploited to help overcome drug resistance.
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| http://dx.doi.org/10.1080/2162402X.2014.998119 | DOI Listing |
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