Characterization of nonmelanoma skin cancer for light therapy using spatial frequency domain imaging.

Biomed Opt Express

Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY, USA ; Department of Biomedical Engineering, University at Buffalo, Buffalo, NY, USA.

Published: May 2015

The dosimetry of light-based therapies critically depends on both optical and vascular parameters. We utilized spatial frequency domain imaging to quantify optical and vascular parameters, as well as estimated light penetration depth from 17 nonmelanoma skin cancer patients. Our data indicates that there exist substantial spatial variations in these parameters. Characterization of these parameters may inform understanding and optimization of the clinical response of light-based therapies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467704PMC
http://dx.doi.org/10.1364/BOE.6.001761DOI Listing

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