AI Article Synopsis
- * Results showed that a high body surface area (BSA), tall stature, and excess weight increased the risk of thyroid cancer, particularly noting that women with higher body fat percentages were at greater risk.
- * However, no significant connection was found between body mass index (BMI) and thyroid cancer risk, pointing to the need for further research to understand the biological mechanisms behind these associations.
Article Abstract
The incidence of thyroid cancer has risen over the past decade, along with a rise in obesity. We studied the role of anthropometric risk factors for differentiated thyroid cancer at the time of diagnosis and at age 20 years in a case-control study conducted in eastern France between 2005 and 2010. The study included 761 adults diagnosed with differentiated thyroid cancer before 35 years of age between 2002 and 2006. They were matched with 825 controls from the general population. Odds ratios were calculated using conditional logistic regression models and were reported for all participants, those with papillary cancer only, and women only. The risk of thyroid cancer was higher for participants with a high body surface area (BSA), great height, or excess weight and for women with a high body fat percentage. Conversely, no significant association was found between body mass index and the risk of thyroid cancer. In the present study, we provide further evidence of the role of BSA and excess weight in the risk of thyroid cancer. These epidemiologic observations should be confirmed by further exploration of the biological mechanisms responsible for the associations of obesity and BSA with thyroid cancer.
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| http://dx.doi.org/10.1093/aje/kwv048 | DOI Listing |
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