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Surgical Excision and Radiotherapy for Giant Keloids in Auricula: A Case Report.
Int Med Case Rep J
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Keloids are characterized by excessive growth of fibrous tissue resulting from abnormal wound-healing processes. They may lead to functional impairments, aesthetic deformities, pruritus, and a decreased quality of life. Various therapies, including intralesional corticosteroid injections, cryotherapy, laser therapy, surgical excision, and radiotherapy, have been used to manage keloids, but the recurrence rates remain high.
View Article and Find Full Text PDFWound healing: insights into autoimmunity, ageing, and cancer ecosystems through inflammation and IL-6 modulation.
Front Immunol
December 2024
Institute of Anatomy, First Faculty of Medicine, Charles, University, Prague, Czechia.
Wound healing represents a complex and evolutionarily conserved process across vertebrates, encompassing a series of life-rescuing events. The healing process runs in three main phases: inflammation, proliferation, and maturation/remodelling. While acute inflammation is indispensable for cleansing the wound, removing infection, and eliminating dead tissue characterised by the prevalence of neutrophils, the proliferation phase is characterised by transition into the inflammatory cell profile, shifting towards the prevalence of macrophages.
View Article and Find Full Text PDFKeloid Formation and Any Skin Complications in Patients Treated With Isotretinoin and Undergone Any Skin-Related Procedures.
J Cosmet Dermatol
November 2024
Department of Dermatology, Rasool Akram Medical Complex Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Background: Isotretinoin is widely used for moderate to severe acne vulgaris. Despite its broad application, isotretinoin carries a risk of permanent scarring and keloid formation following various skin procedures. As a result, a delay of at least 6-12 months after completing or discontinuing isotretinoin treatment is commonly recommended before undergoing skin procedures.
View Article and Find Full Text PDFUse of Postoperative Radiotherapy and Multiple Adjuvant Treatments After Surgical Removal of a Giant Retroauricular Keloid in a Pediatric Patient.
Pediatr Dermatol
November 2024
Department of Dermatology, Hospital Sant Joan de Déu, Barcelona, Catalonia, Spain.
The use of postoperative radiotherapy (PORT) for the treatment of keloids in the pediatric population is rare, despite being a common pathology at this age. Recurrences after surgery are very common. The absence of a standardized protocol for the management of recurrent keloids further complicates therapeutic decision-making.
View Article and Find Full Text PDFA Subunit-Based Concept for Preoperative Design of the Cauliflower Ear.
J Craniofac Surg
September 2024
Department of Plastic Surgery, The Second Affiliated Hospital of Harbin Medical University, Nangang District, Harbin, Heilongjiang Province.
Purpose: Cauliflower ear is an ear deformity caused by a closed ear injury with varying severity. Several studies on the systematic reconstruction of cauliflower ear have been reported. Here, the authors aim to introduce a simplified subunit-based reconstruction concept for the cauliflower ear.
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