Objective: To report reproductive outcomes in women who underwent radiofrequency volumetric thermal ablation (RFVTA) of symptomatic uterine fibroids.
Study Design: Retrospective analysis of fibroid characteristics, treatment parameters, and pregnancy outcomes of 6 subjects in 3 prospective trials of laparoscopic ultrasound-guided RFVTA.
Results: Despite the requirement that women enrolled in the RFVTA studies did not desire current or future childbearing and were to continue contraception, 6 subjects conceived at between 3.5 and 15 months postreatment. The number of fibroids treated per patient ranged from 1 to 7, measured between 1.0 cm and 7.6 cm at the greatest diameter, and included multiple types (submucosal, intramural, transmural, and subserosal). Five patients (5/6, 83%) delivered full-term healthy infants: 1 by vaginal delivery and 4 by cesarean section. One patient (1/6, 17%) had a spontaneous miscarriage in the first trimester.
Conclusion: Viable, full-term pregnancies are possible after RFVTA. Further, in-depth study of pregnancy outcomes following laparoscopic ultrasound-guided radiofrequency, volumetric ablation of fibroids is warranted.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Histologic Effects of Fractional Lasers and Energy-Based Devices on Intradermally Injected Hyaluronic Acid Filler for Improving Skin Smoothness.
Lasers Surg Med
November 2024
Maryland Laser, Skin, and Vein Institute, Hunt Valley, Maryland, USA.
Background: Prior studies have shown that energy-based devices (EBDs) over pre-injected hyaluronic acid (HA) fillers do not significantly affect clinical outcomes. However, the impact of EBDs over newly FDA-approved HA filler for improving skin smoothness is still undetermined.
Objective: To evaluate the immediate histologic changes after various popular EBDs are performed over pre-injected, newly FDA-approved intradermal HA filler.
Physical vitrification and nanowarming at human organ scale to enable cryopreservation.
bioRxiv
November 2024
Department of Mechanical Engineering, University of Minnesota, Minneapolis, USA.
Organ banking by vitrification could revolutionize transplant medicine. However, vitrification and rewarming have never been demonstrated at the human organ scale. Using modeling and experimentation, we tested the ability to vitrify and rewarm 0.
View Article and Find Full Text PDFParallel-transmission spatial spectral pulse design with local specific absorption rate control: Demonstration for robust uniform water-selective excitation in the human brain at 7 T.
Magn Reson Med
March 2025
Center for Magnetic Resonance Research, Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA.
Purpose: To propose a novel method for parallel-transmission (pTx) spatial-spectral pulse design and demonstrate its utility for robust uniform water-selective excitation (water excitation) across the entire brain.
Theory And Methods: Our design problem is formulated as a magnitude-least-squares minimization with joint RF and k-space optimization under explicit specific-absorption-rate constraints. For improved robustness against off-resonance effects, the spectral component of the excitation target is prescribed to have a water passband and a fat stopband.
Microwave versus Radiofrequency Ablation in Treating Predominantly Solid Benign Thyroid Nodules: A Randomized Controlled Trial.
Radiology
October 2024
From the Department of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital, No. 100 W Fourth Ring Rd, Beijing 100039, China (S.C., J.D., Y. Cang, J.Y., P.L.); Chinese PLA Medical School, Beijing, China (S.C., Y. Cang); Department of Ultrasound, First Affiliated Hospital of Dalian Medical University, Dalian, China (Y. Che); Department of Ultrasound, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (G.D.); Department of Ultrasound, Lishui People's Hospital, Lishui, China (C.Z.); Department of Interventional Ultrasound, Zhejiang Cancer Hospital, Hangzhou, China (D.X.); and Department of Statistics, Guilin Gooclin Technology, Guilin, China (Q.L.).
Background Current guidelines recommend radiofrequency ablation (RFA) as the first-line treatment for benign thyroid nodules. Purpose To compare the efficacy and safety of microwave ablation (MWA) and RFA for the treatment of predominantly solid benign thyroid nodules. Materials and Methods This prospective, randomized, open-label, multicenter study was conducted from August 2019 to February 2023.
View Article and Find Full Text PDFVolumetric lesion analysis and validation of various bipolar configurations in radiofrequency ablation of ventricular myocardium in a bovine model.
J Interv Card Electrophysiol
October 2024
Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, 695011, India.
Article Synopsis
- The study investigates the effectiveness of bipolar radiofrequency ablation (B-RFA) compared to conventional methods, focusing on how different configurations and settings impact lesion formation and minimize complications like steam pops.
- A custom ex-vivo model tested lesion outcomes under various power levels and catheter orientations, showing that lesions created with a true parallel configuration had significantly fewer steam pops and better tissue penetration (transmurality).
- Findings suggest that using a 30 W to 40 W power setting and maintaining at least 15 mm distance between electrodes enhances safety and effectiveness in B-RFA procedures.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!