Rhodium-catalyzed alkylation reactions of aromatic C-H bonds in aromatic amides with styrene derivatives have been developed by using an 8-aminoquinoline as a bidentate directing group. C-C bond formation selectively occurred between the ortho C-H bonds in aromatic amides and the terminal carbon of the styrene derivatives. The presence of an 8-aminoquinoline moiety is essential for the success of the reaction.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.5b01682 | DOI Listing |
Publication Analysis
Top Keywords
c-h bonds
12
bonds aromatic
12
aromatic amides
12
rhodium-catalyzed alkylation
8
styrene derivatives
8
alkylation c-h
4
aromatic
4
amides styrenes
4
styrenes bidentate-chelation
4
bidentate-chelation assistance
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!