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http://dx.doi.org/10.1503/cmaj.150329 | DOI Listing |
Therapie
October 2024
Centre d'Évaluation et d'Information sur la Pharmacodépendance - Addictovigilance, Service de pharmacologie médicale, CHU de Bordeaux, 33000 Bordeaux, France; Université de Bordeaux, Inserm, Bordeaux Population Health Research Centre, Team, Pharmacoepidemiology, UMR 1219, 33000 Bordeaux, France. Electronic address:
Introduction: Analgesics are among the most widely used drugs worldwide. The French Addictovigilance Network (FAN) established the antalgiques stupéfiants et ordonnances sécurisées (ASOS [narcotic analgesics and secure prescriptions]) survey in order to assess the dissemination of tamper-resistant prescription forms for narcotic analgesic within the medical community, as well as the nature and evolution of the prescriptions. After outlining the missions of the FAN, this article will describe the population treated with narcotic analgesics in France, their therapeutic indications and how the data have evolved since 2007.
View Article and Find Full Text PDFAAPS PharmSciTech
September 2022
Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Ganpat Vidyanagar, Mehsana-Gozaria Highway, Kherva, Mehsana, Gujarat, 384012, India.
Pharmaceutical opioid dosage forms are commonly misused via an oral route in non-manipulated form, i.e., overdose in intact form, or manipulated form, i.
View Article and Find Full Text PDFInt J Drug Policy
November 2022
British Columbia Centre on Substance use, Vancouver, BC, Canada, V6Z 2A9; Department of Medicine, University of British Columbia, Vancouver, BC, Canada, V6Z 1Y6.
Background: OxyContin was delisted from Canadian provincial drug formularies in March 2012 and replaced with a reformulated tamper-resistant form of oxycodone (i.e., OxyNeo).
View Article and Find Full Text PDFNihon Yakurigaku Zasshi
May 2021
Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital.
In Japan, 14 opioids with a variety of dosage forms, such as oral preparation, injection, transdermal patch, transmucosal and suppository are clinically available as analgesics, and their use properly depends on the type and degree of pain and patient condition. Fundamentally, strong opioids are restricted to only treatment of cancer pain, while the indication of fentanyl transdermal patch and oxycodone tamper resistant tablet has been expanded for the treatment of non-cancer chronic pain. In US, the additional indication of opioids to chronic pain has led to prolongation and generalization of opioid use, which may contribute to "opioid crisis" in which opioid-related death strikingly increased due to opioid abuse and overdose-induced respiratory depression.
View Article and Find Full Text PDFBr J Clin Pharmacol
April 2021
Rocky Mountain Poison and Drug Safety, Denver Health and Hospital Authority, Denver, Colorado.
Aims: Prescription drug misuse in the USA increased during the 1990s to 2010. The epidemic stimulated the need new analytical strategies and techniques to understand the medications involved, user characteristics and other factors needed to address the epidemic.
Methods: A strategy of mosaic surveillance has evolved.
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