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Frequency locked whispering evanescent resonator (FLOWER) for biochemical sensing applications.
Nat Protoc
January 2025
Wyant College of Optical Sciences, The University of Arizona, Tucson, AZ, USA.
Sensitive, rapid and label-free biochemical sensors are needed for many applications. In this protocol, we describe biochemical detection using FLOWER (frequency locked optical whispering evanescent resonator)-a technique that we have used to detect single protein molecules in aqueous solution as well as exosomes, ribosomes and low part-per-trillion concentrations of volatile organic compounds. Whispering gallery mode microtoroid resonators confine light for extended time periods (hundreds of nanoseconds).
View Article and Find Full Text PDFDeep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks.
Sci Rep
January 2025
Department of Computer Engineering, Inha University, Incheon, Republic of Korea.
The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients' overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas.
View Article and Find Full Text PDFAn Electroglottographic and Acoustic Study on Mandarin Speech in Male Heroin Users.
J Voice
January 2025
Department of Audio, Video, and Electronic Forensics, Academy of Forensic Science, Shanghai, China; Shanghai Forensic Service Platform, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai, China.
Drug abuse can cause severe damage to the human speech organs. The vocal folds are one of the important speech organs that produce voice through vibration when airflow passes through. Previous studies have reported the negative effects of drugs on speech organs, including the vocal folds, but there is still limited research on relevant field.
View Article and Find Full Text PDFGold nanoparticle-modified single-walled carbon nanotube terahertz metasurface for ultrasensitive sensing of trace proteins.
Talanta
January 2025
State Key Laboratory of Materials for Integrated Circuits, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China.
Research on metasurface sensors with high sensitivity, strong specificity, good biocompatibility and strong integration is the key to promote the application of terahertz waves in the field of biomedical detection. However, traditional metallic terahertz metasurfaces have shortcomings such as poor biocompatibility and large ohmic loss in the terahertz frequency band, impeding their further application and integration in the field of biosensing detection. Here, we overcome this challenge by proposing a high-performance terahertz metasurface based on gold nanoparticles and single-walled carbon nanotubes composite film.
View Article and Find Full Text PDFOptimization of parallel coiled cavities of different depths in microperforated panel sound absorbers.
Sci Rep
January 2025
Key Laboratory of Urban and Architectural Heritage Conservation, Ministry of Education, School of Architecture, Southeast University, 2# Sipailou, Nanjing, 210096, China.
This paper presents a microperforated panel (MPP) sound absorber with parallel coiled-up-cavities of different-depths (PCD) and the corresponding optimization on their cavities. In this study, an analytical model is initially proposed for estimating the cavity depths of the PCD-MPP absorber upon normal incidence absorption coefficient evaluation at given resonance frequencies. Cavity effective depths and normal incidence absorption coefficient are evaluated after coiling up cavities for a compact structure.
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