330 boys with acute leukemia treated from 1978 to 1987 are reported. Of these patients, 24 (7.3%) developed testicular leukemia and 23 were treated by local irradiation with doses of 20-50 Gy on both sides of the testis. Swollen testis returned to normal size at the end of therapy in 10 patients whereas 13 still had enlarged testis. 18 patients were followed for 3-75 months with a mean survival time of 16.8 months. The incidence, treatment, dose of radiation, and results of therapy of testicular leukemia in children are discussed and biopsy of testis is suggested.
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