VITREOMACULAR TRACTION AFTER DEXAMETHASONE INTRAVITREAL IMPLANT (OZURDEX) INJECTION: THE EFFECT OF ANOMALOUS POSTERIOR VITREOUS DETACHMENT.

Retin Cases Brief Rep

*Department of Ophthalmology, University of California, San Francisco, San Francisco, California; and †Department of Ophthalmology, Bhumibol Adulyadej Hospital, Royal Thai Air Force, Bangkok, Thailand.

Published: September 2016

Purpose: To describe an unusual macular complication after dexamethasone intravitreal implant (Ozurdex) injection.

Methods: Case history and macular optical coherence tomography findings are described. The report describes a patient with proliferative diabetic retinopathy and vitreoschisis who received Ozurdex treatment for diabetic macular edema.

Results: After Ozurdex injection, visual acuity worsened because of newly formed vitreomacular traction that was demonstrated on optical coherence tomography imaging. A mechanism is proposed by which the medication might have contributed to this outcome.

Conclusion: In this patient with vitreoschisis, a thickened posterior hyaloid membrane and traction developed after Ozurdex injection. The authors recommend careful evaluation of the macula before injection, particularly in diabetic patients with vitreoschisis.

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Source
http://dx.doi.org/10.1097/ICB.0000000000000172DOI Listing

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