From rhizomes of Panax japonicus (Araliaceae), two polysaccharides named tochibanan-A and -B, which show reticuloendothelial-potentiating activity in the carbon clearance test in mice, were isolated. The structure of tochibanan-A (molecular mass: 23,000) was elucidated as a linear beta-1,4-D-galactan. Tochibanan-B (molecular mass: 40,000) consists of D-galactose (87.1%), L-arabinose, D-glucose and D-galacturonic acid and has a beta-D-(1----4)-linked galactopyranosyl backbone possessing GalA-(1----6)-Gal, Ara-(1----5)-Ara, Gal, and Glc side chains. The structure around the branching points and the repeating unit were investigated and a possible structure of tochibanan-B is proposed.

Download full-text PDF

Source
http://dx.doi.org/10.1248/cpb.37.2587DOI Listing

Publication Analysis

Top Keywords

rhizomes panax
8
panax japonicus
8
molecular mass
8
reticuloendothelial system-activating
4
system-activating polysaccharides
4
polysaccharides rhizomes
4
japonicus tochibanan-a
4
tochibanan-a rhizomes
4
japonicus araliaceae
4
araliaceae polysaccharides
4

Similar Publications

Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance.

Chin J Nat Med

January 2025

Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China. Electronic address:

Astragali Radix (AR) and Notoginseng Radix et Rhizoma (NR) are frequently employed in cardiovascular disease treatment. However, the efficacy of the AR-NR medicine pair (AN) in improving cardiac remodeling and its underlying mechanism remains unclear. This study aimed to evaluate AN's cardioprotective effect and potential mechanism on cardiac remodeling using transverse aortic constriction (TAC) in mice and angiotensin II (Ang II)-induced neonatal rat cardiomyocytes (NRCMs) and fibroblasts in vitro.

View Article and Find Full Text PDF

Ginseng Radix et Rhizoma and its preparations are often adulterated with Panacis Quinquefolii Radix. Based on the research on Ginseng Radix et Rhizoma and Panacis Quinquefolii Radix, the causes and analytical method of adulteration were determined. A UPLC-MS/MS method was developed for the detection of Panacis Quinquefolii Radix mixed in Ginseng Radix et Rhizoma, with pseudoginsenoside F_(11) as the marker.

View Article and Find Full Text PDF

Ginsenosides and lipids are both bioactive ingredients for ginseng. Targeting these two categories of components, this study was designed to develop desorption electrospray ionization-mass spectrometry imaging approaches and spatial metabolomics strategies, achieving the visualization and differentiation among different parts of root (e.g.

View Article and Find Full Text PDF
Article Synopsis
  • Panax ginseng, a commonly used herbal medicine in Asia, relies on its roots and rhizomes, which contain ginsenosides, the main active compounds that enhance its adaptability to ecological stress.
  • A study involved applying water spray to create a short-term water stress scenario for 5-year-old P. ginseng roots, revealing significant increases in oxidative stress indicators and enzyme activities linked to ginsenoside production.
  • The water stress treatment resulted in notable boosts in various ginsenosides (e.g., Rg1 and Rb1) and a 40.1% increase in total saponins, highlighting the potential for water management to enhance the medicinal properties of P. ginseng.
View Article and Find Full Text PDF

The Adaptive Mechanism of Ginseng Rhizomes in Response to Habitat Changes.

Curr Issues Mol Biol

October 2024

Co-constructing Key Laboratory by Province and the Ministry of Science and Technology of Ecological Restoration and Ecosystem Management, College of Chinese Medicinal Material, Jilin Agricultural University, Changchun 130118, China.

Article Synopsis
  • Ginseng, a medicinal plant, has two cultivation methods in China (under-forest and farmland), which affect its rhizome characteristics and economic value.
  • * A study transplanted two-year-old ginsengs into different habitats (farmland and forests) to examine how these environments influence rhizome morphology, revealing significant differences in growth due to light and soil nutrients.
  • * Findings showed rhizomes in forest settings were significantly longer and had changes in hormone levels and gene expression related to elongation, highlighting ginseng's ability to adapt morphologically to different habitats.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!