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Effects of Combined Intrathecal Mesenchymal Stem Cells and Schwann Cells Transplantation on Neuropathic Pain in Complete Spinal Cord Injury: A Phase II Randomized Active-Controlled Trial.
Cell Transplant
January 2025
Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Neuropathic pain is a debilitating complication following spinal cord injury (SCI). Currently, effective treatments for SCI-induced neuropathic pain are highly lacking. This clinical trial aimed to investigate the efficacy of combined intrathecal injection of Schwann cells (SCs) and bone marrow-derived mesenchymal stem cells (BMSCs) in improving SCI-induced neuropathic pain.
View Article and Find Full Text PDFTemperature Exposure and Psychiatric Symptoms in Adolescents From 2 European Birth Cohorts.
JAMA Netw Open
January 2025
ISGlobal, Barcelona, Spain.
Importance: Climate change can adversely affect mental health, but the association of ambient temperature with psychiatric symptoms remains poorly understood.
Objective: To assess the association of ambient temperature exposure with internalizing, externalizing, and attention problems in adolescents from 2 population-based birth cohorts in Europe.
Design, Setting, And Participants: This cohort study analyzed data from the Dutch Generation R Study and the Spanish INMA (Infancia y Medio Ambiente) Project.
Dermatologists' knowledge, attitudes, and practices regarding omalizumab therapy for chronic urticaria.
Arch Dermatol Res
January 2025
Department of dermatology, Lishui Central Hospital, Lishui, 323000, China.
The purpose of this study was to evaluate dermatologists' knowledge, attitudes, and practices (KAP) concerning omalizumab therapy for chronic urticaria. We conducted a cross-sectional study in several hospitals in China, mainly in hospitals in Zhejiang Province, during August 1, 2024 - August 15, 2024 using a self-administered KAP questionnaire. Wilcoxon-Mann-Whitney tests and Kruskal-Wallis analysis of variance were performed to compare differences across groups Factors influencing practice were determined through multivariable logistic regression.
View Article and Find Full Text PDFComparison of different treatment positions of nerve slider technique for patients with low back pain: a randomized control trial.
Eur J Phys Rehabil Med
January 2025
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, European University of Lefke, Mersin, Türkiye.
Background: Low back pain (LBP) accompanied by sciatica is a widespread musculoskeletal issue with multifactorial etiology, impacting individuals across various demographics. Conservative treatments, notably physiotherapy, are key in managing LBP with sciatica, with neural mobilization techniques emerging as beneficial adjuncts.
Aim: This research aims to assess the effectiveness of utilizing the sciatic slider technique (SST) in both supine and slump positions, compared to conventional physiotherapy alone, in alleviating pain severity, improving lumbar flexibility, lumbar lordosis, lower limb muscle strength, and functional ability in patients with LBP associated with sciatica.
A comparative analysis of older patients with chewing difficulties due to temporomandibular disorders and tooth loss.
J Dent Sci
January 2025
Department of Oral Medicine, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Background/purpose: Chewing difficulty can contribute to psychological stress, which reduces the quality of life for older adults. The purpose of this study was to investigate and analyze the severity of masticatory discomfort, stress response, and sleep disturbance in older patients experiencing masticatory discomfort due to tooth loss or temporomandibular disorders (TMD), to find the further treatment direction for these patients.
Materials And Methods: A total of 392 patients aged 50 years and older with mastication difficulties were analyzed.
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