Bacillus Calmette-Guérin (BCG) therapy is often associated with side effects. The most feared is disseminated sepsis that may occur rarely with the development of mycotic aortic aneurysms. Twenty cases of patients treated with intravesical BCG complicated by mycotic abdominal aortic aneurysm have been reported in the literature, including 2 cases of the present study. Delayed vascular work-up represents a critical aspect. Mycotic aneurysms evidence a rapid progression. Primary care physicians and urologists should be sensitized to recognize unspecified symptoms such as potential clinical manifestations of a mycotic abdominal aortic aneurysm, even several months or years after BCG therapy.
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http://dx.doi.org/10.1016/j.avsg.2015.01.036 | DOI Listing |
Radiol Case Rep
February 2025
Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
Mycotic aneurysms are a rare but potentially life-threatening complication of infections, particularly those involving the spine. Spondylodiscitis, a bacterial or fungal infection of the intervertebral disc, is a known risk factor for the development of mycotic aneurysms. Early diagnosis and prompt treatment are crucial for improving patient outcomes.
View Article and Find Full Text PDFFront Cardiovasc Med
November 2024
National Research Oncology Center, Astana, Kazakhstan.
Background: Rupture of an abdominal aortic aneurysm (AAA) is a life-threatening emergency, with untreated cases nearing a 100% mortality rate. This case presents a rare complication of AAA rupture with an infected retroperitoneal hematoma, emphasizing the importance of timely diagnosis and a multidisciplinary approach.
Case Presentation: A 59-year-old male presented with lower back pain, fever, and difficulty moving, persisting for three weeks.
Acta Trop
December 2024
Department of Medicine, Cairns Hospital, Cairns, Queensland, Australia; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia. Electronic address:
Since 2019, Burkholderia pseudomallei has been the most common cause of mycotic aneurysm at Cairns Hospital in tropical Australia. Among 233 culture-confirmed cases of melioidosis since this time, 8 (3.4 %) were diagnosed with a mycotic aneurysm.
View Article and Find Full Text PDFCureus
October 2024
Paediatric Cardiology, Uganda Heart Institute, Kampala, UGA.
Int J Surg Case Rep
December 2024
Department of Vascular Surgery, Royal Perth Hospital, Perth, Australia.
Introduction: Melioidosis is caused by Burkholderia pseudomallei and primarily affects non-vascular organ systems. We present a case of a melioidotic penetrating aortic ulcer (PAU) with unusual clinical features of vascular infection. The patient was successfully treated with a single-stage neoaortoiliac system procedure, highlighting the challenges in managing melioidotic aortic infections.
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