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Why I Discourage "ED Course" in Oral Patient Presentations.
J Gen Intern Med
January 2025
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Trainees frequently present data, including vital signs, laboratory test results, and imaging results, just after the history or presenting illness in a section labeled "ED Course." This practice distracts from the history and physical and decenters the patient as the most valuable source of diagnostic data. Reformatting presentations to appropriately present objective data after the complete history may improve diagnosis and refocuses attention on the patient.
View Article and Find Full Text PDFPsychopathology trajectories and relapse in first episode schizophrenia with assured long-acting injectable adherence over 24 months.
Schizophr Res
January 2025
Faculty of Medicine and Health Sciences, Department of Psychiatry, Stellenbosch University, Tygerberg, 7500 Cape Town, South Africa.
Background: Relapse following a first episode of schizophrenia (FES) is common and often results in serious adverse psychosocial consequences. Treatment non-adherence is a key risk factor for relapse, but why relapse occurs despite antipsychotic treatment adherence remains unclear. This study examined the differences in FES psychopathology trajectories over 24-months with assured long-acting injectable antipsychotic (LAIA) treatment, to control for treatment adherence between those who relapsed and those who did not and what moderates these group differences.
View Article and Find Full Text PDFDanish parents' vaccination readiness is associated with their children's officially registered vaccination history.
Vaccine
January 2025
Department of Psychology, University of Copenhagen, Copenhagen, Denmark; Copenhagen Center for Social Data Science (SODAS), University of Copenhagen, Copenhagen, Denmark; Faculty of Psychology, University of Vienna, Vienna, Austria.
Previous research has shown that parents' vaccination readiness, as measured by the 7C vaccination readiness scale, helps to understand whether and why parents are (not) willing to vaccinate their children. However, there is a lack of research investigating the association between parents' vaccination readiness and their children's actual vaccine uptake. Addressing this gap, we examined how Danish parents' level of vaccination readiness is associated with their child's vaccination status combining survey with official registry data.
View Article and Find Full Text PDFFormal Thought Disorder in Schizophrenia: A Problematic History.
Schizophr Bull
January 2025
Department of Psychiatry, University of Oxford, and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX37JX, United Kingdom.
Background And Hypothesis: Formal thought disorder (FTD), studied even before the inception of the concept of schizophrenia, remains a deeply isolating experience for patients as well as a difficult one for their interlocutors, including clinicians.
Study Design: The views on language, paralinguistic, and extralinguistic features exhibited by patients with severe mental ill health are reviewed, including the contributions from 19th-century European authors to the last third of the 20th century.
Study Results: Stages in the construction of FTD are described, including its merging with Dementia Praecox, and its subsequently being shaped by notions such as primitive archaic thinking, paralogical or autistic thinking, concretism, overinclusive thinking, and the return of the efforts to describing it with increased reliability.
Longitudinal Treatment Patterns of Chorea in North American Patients with Huntington's Disease: Data from Enroll-HD.
Neurol Ther
January 2025
Health Economics and Outcomes Research, Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA, 92130, USA.
Introduction: Chorea is the primary manifestation of Huntington's disease. Different clinicians pursue varied approaches to chorea management, and real-world evidence describing them is needed. The objective of this study was to assess the presence and severity of chorea, chorea pharmacotherapy, and treatment practice, and patterns in a large natural-history cohort with Huntington's disease.
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