Objective: Physical activity (PA) adoption can improve quality of life (QOL) and related outcomes among breast cancer survivors. To disseminate a telephone-based PA intervention to cancer survivors, we partnered with the American Cancer Society's Reach To Recovery program (RTR) whose volunteers (breast cancer survivors) provide information and emotional support to breast cancer survivors.
Method: This randomized controlled trial compared the effects of PA telephone counseling delivered by RTR volunteers (PA Plus RTR) versus a contact control condition (RTR Control) in six New England states. RTR volunteers (n = 18; mean age = 54.9 years, mean years since breast cancer diagnosis = 7.0) delivered a 12-week PA program to help participants adopt 30 min of moderate-intensity activity ≥5 days/week. Breast cancer survivors (n = 76; mean age = 55.62 years, mean years since diagnosis = 1.11, Stage 0 = 6.58%, Stage 1 = 38.16%, Stage 2 = 44.74%, Stage 3 = 10.53%) were randomized to a study group.
Results: Using a series of generalized linear models, we assessed intervention effects on physical health, physical functioning, mental health, fatigue, and QOL at 12 and 24 weeks, and examined whether these effects were moderated by age, marital status, chemotherapy use, and baseline values of the outcomes. There were no significant intervention effects on the outcomes but there were significant moderator effects of age, chemotherapy use, and baseline physical functioning, physical health, and breast cancer-specific symptoms (all p's < .05).
Conclusions: Specific demographic and treatment variables and baseline psychosocial health moderate the impact of PA interventions on QOL. Copyright © 2015 John Wiley & Sons, Ltd.
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http://dx.doi.org/10.1002/pon.3884 | DOI Listing |
PLoS One
January 2025
Aston Institute of Health and Neurodevelopment, Aston University, Birmingham, United Kingdom.
Survivors of pediatric brain tumours are at a high risk of cognitive morbidity. Reliable individual-level predictions regarding the likelihood, degree, and affected domains of cognitive impairment would be clinically beneficial. While established risk factors exist, quantitative MRI analysis may enhance predictive value, above and beyond current clinical risk models.
View Article and Find Full Text PDFAnesth Analg
January 2025
From the Department of Anesthesiology & Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
The number of cancer patients, cancer survivors, and cancer surgeries is expected to continue to grow and anesthesiologists will benefit from having a framework on how to approach treating perioperative pain in the oncologic population. This article presents general considerations for formulating a perioperative pain management plan including cancer-specific contraindications for epidurals and nerve blocks, common procedures for pain after thoracic and abdominal surgeries, and alternative pain management techniques.
View Article and Find Full Text PDFJ Pediatr Psychol
January 2025
Department of Pediatrics, Rutgers Cancer Institute, New Brunswick, NJ, United States.
Objective: Although childhood cancer survivors require lifelong "risk-based" follow-up care, most adult survivors do not receive such care, and many are lost during the transition from pediatric to adult follow-up care. The goal of this study was to evaluate the feasibility and acceptability of the "Managing Your Health" self-management and peer mentoring intervention to improve transition readiness and self-management skills among young adult survivors of childhood cancer.
Methods: Survivors of childhood cancer ages 18-25 years were randomized 1:1 to the Managing Your Health intervention (six video/phone calls with a peer mentor, another young adult survivor, and five online educational modules) or usual care.
J Anesth
January 2025
Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kajii-Cho 465 Kamigyo-Ku, Kyoto, 602-0841, Japan.
Clin Epidemiol
January 2025
Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Purpose: The thyroid gland is an organ at risk in breast cancer survivors who receive radiation therapy to the supraclavicular lymph nodes. We investigated the effect of radiation dose to the thyroid gland on the incidence of hypothyroidism in early-stage breast cancer patients treated with CT-guided radiation therapy.
Patients And Methods: We recruited women aged ≤75 years diagnosed with breast cancer from March 2016 through August 2017 at Odense University Hospital, Denmark.
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