Aims: The aims of study were to examine the antibacterial potential of two commercial essential oils (EOs) from coriander (Coriandrum sativum L.) and thyme (Thymus vulgaris L.) against vaginal clinical strains of bacteria and yeast and their chemical composition.
Methods And Results: Antimicrobial activities of commercial essential oils were determined using macro-diffusion (disc, well) and micro-dilution method in 96-well micro plates against twelve clinical strains of bacteria: Escherichia coli, Proteus mirabilis, Staphylococcus aureus and Enterococcus sp., Staph. aureus ATCC 25923, ATCC 6538 and E. coli 25922 and two clinical Candida albicans strains, including ATTC 10231. Spectrophotometric method was used for determination on C. albicans growth. An antimicrobial effect of EOs was strain specific. Bactericidal activity was higher for coriander EO (minimal inhibitory concentration (MICs) 0·4-45·4 μl ml(-1)) against almost all tested bacteria, except multiple resistant strains of Eneterococcus sp. and Proteus sp. Thyme EO showed slightly better fungicidal activity reaching MIC at 0·11 mg ml(-1) for all C. albicans strains. The effect of EOs on biofilm-forming ability was tested for two strains of Staph. aureus and E. coli, as well as on C. albicans filamentation ability. Brine shrimp lethality bioassay revealed thymus oil total toxicity and coriander oil intoxicity (LC50 = 2·25 mg ml(-1)). The chemical composition of oils was analysed by gas chromatography mass spectrometry showing oxygenated monoterepenes as dominant constituents.
Conclusions: The results provide in-vitro scientific support for the safety possible use of Coriander EO against E. coli, Staph. aureus and C. albicans vaginal infections in alternative gynaecological treatment.
Significance And Impact Of Study: To examine EOs as possible constituent of naturally based antimicrobial agents in vaginaletes for safety gynaecological application.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jam.12883 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of nanoemulsion of Ajwain-cardamom essential oils on Mortadella sausage quality during chilling (4°C) storage.
Heliyon
January 2025
Department of Chemistry, Quchan Branch, Islamic Azad University, Quchan, Iran.
Essential oils application as natural preservatives is challenging owning to low solubility and stability to harsh conditions, while incorporation of essential oils into nanoemulsion systems can effectively improve these issues. Therefore, the nanoemulsion of () and cardamom essential oils were fabricated through self-emulsification technique and evaluated their size, ζ-potential, antioxidative and antibacterial activities. The effect of double nanomulsion on the textural and sensorial properties of Mortadella sausage was also examined under chilling temperature (4 °C).
View Article and Find Full Text PDFExploring Chemical Profiles, Antifeedant, Nematicidal and Phytotoxic Potentials of Seven Essential Oils from Eucalyptus Species.
Chem Biodivers
January 2025
INRGREF: Institut National de Recherche en Genie Rural Eaux et Forets, Forestry, Tunis, Tunis, TUNISIA.
Leaf essential oils (EOs) of seven Eucalyptus species from southern Tunisia (E. gracilis, E. lesouefii, E.
View Article and Find Full Text PDFUltrasonic emulsification of Cananga odorata nanoemulsion formulation for enhancement of herbicidal potential.
Sci Rep
January 2025
School of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok, 10520, Thailand.
A nanoemulsion was fabricated from Cananga odorata essential oil (EO) and stabilized by incorporation of Tween 80 using ultrasonication. The major constituents of the EO were benzyl benzoate, linalool, and phenylmethyl ester. Differing sonication amplitude (20-60%) and time (2-10 min) were assessed for effects on nanoemulsion droplet size and polydispersity index (PI).
View Article and Find Full Text PDFAnti-inflammatory activity of essential oil from medicinal plants: An insight into molecular mechanism, in-silico studies and signaling pathways.
Phytomedicine
January 2025
Centre for Industrial Biotechnology Research, Siksha 'O' Anusandhan Deemed to be University, Campus 2, Kalinganagar, Bhubaneswar-751003, Odisha, India. Electronic address:
Background: Medicinal plants have historically been the cornerstone of treatment for a myriad of ailments. With modern pharmacology, many contemporary drugs have been derived from traditional medicine practices. Essential oils from these plants, known for their anti-inflammatory capabilities, have played a significant role in treating conditions such as cardiovascular and inflammatory skin diseases, as well as joint inflammation.
View Article and Find Full Text PDFAn unconventional separation method of α-Terpineol from its isomer 1,8-Cineole via in situ-association formation of deep eutectic solvent and machine learning.
J Chromatogr A
January 2025
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, PR China. Electronic address:
α-Terpineol and 1,8-cineole are two important compounds in essential oils. This study developed an efficient method to recover α-terpineol from model oil (MO) based on association extraction by in situ formations of deep eutectic solvent (DES) between α-terpineol and some quaternary ammonium salts (QASs) by hydrogen-bond (HB) interaction. Such interaction could be broken almost completely by the introduction of water, due to the stronger HB interaction between water and QASs, which could release α-terpineol by liquid-liquid separation and save the organic solvents consumption.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!