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Characterization of Phlorotannins from Brown Algae by LC-HRMS. | LitMetric

Characterization of Phlorotannins from Brown Algae by LC-HRMS.

Methods Mol Biol

Measurement Science and Standards, National Research Council of Canada, 1200 Montreal Road, Ottawa, ON, Canada, K1A 0R6,

Published: March 2016

Phlorotannins are a class of polyphenols found in brown seaweeds that have significant potential for use as therapeutics, owing to their wide range of bioactivities. Molecular characterization of phlorotannin-enriched extracts is challenging due to the extreme sample complexity and the wide range of molecular weights observed. Herein, we describe a method for characterizing phlorotannins employing ultrahigh-pressure liquid chromatography (UHPLC) operating in hydrophilic interaction liquid chromatography (HILIC) mode combined with high-resolution mass spectrometry (HRMS).

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Source
http://dx.doi.org/10.1007/978-1-4939-2684-8_16DOI Listing

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