We used intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) to explore the possibility of preoperative diagnosis of soft tissue tumors (STTs). This prospective study enrolled 23 patients. Conventional MRI and IVIM examinations were performed on a 3.0T MR imager. Eight (35%) hemangiomas, 11 (47%) benign soft tissue tumors excluding hemangiomas (BSTTEHs) and 4 soft tissue sarcomas (STSs) were assessed. The mean tumor size was about 1652.36 ± 233.66 mm(2). Ten b values (0-800 s/mm(2)) were used to evaluate diffusion and perfusion characteristics of IVIM. IVIM parameters (ADC(standard), ADC(slow), ADC(fast), and f) of STTs were measured and evaluated for differentiating hemangiomas, BSTTEHs, and STSs. ADC(slow) and ADC(fast) value were different for hemangiomas, BSTTEHs, and STSs separately (P < 0.001, P < 0.001, and P = 0.001). ADC(slow), cut-off value smaller than 0.93 × 10(-3) mm(2)/s, was the best parameter to differ STSs (0.689 ± 0.173 × 10 (-3)mm(2)/s) from hemangiomas (0.933 ± 0.237 × 10 (-3)mm(2)/s) and BSTTEHs (1.156 ± 0.120 × 10 (-3)mm(2)/s) (P = 0.001). ADC(slow) (0.93 × 10(-3) mm(2)/s
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504541 PMC http://dx.doi.org/10.1097/MD.0000000000001028 DOI Listing Publication Analysis
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