Eye Popping Disease: Common Characteristics and Management of Spontaneous Globe Subluxation.

Purpose: The objective of this study was to describe the clinical features, predisposing factors, and management of 8 new cases of spontaneous globe subluxation (SGS) and provide a review of the relevant literature.

Design: Patient demographics, clinical presentations, investigations, management, complications, and outcomes were measured.

Methods: This was a retrospective, case-note analysis of 8 patients with SGS and a major review of the English-language literature.

Results: Eight new cases of spontaneous globe subluxation were identified with varying clinical manifestations and treatments. Literature review has shown less than 50 cases. Space-occupying lesions such as thyroid eye disease, shallow orbits, and floppy eyelids were major contributors to predisposition to SGS.

Conclusions: Orbital congestion, shallow orbits, and floppy eyelids can all play a role in predisposing patients to SGS. Successful surgical management of SGS, when required, should be tailored to the individual patient profile for best results.