AI Article Synopsis
- Preeclampsia is a pregnancy-related condition that can lead to serious health issues for both mother and baby, including mortality and morbidity.
- Oxidative stress is considered a key factor in the development of preeclampsia, disrupting normal blood flow and causing issues with placentation.
- Research has focused on how oxidative damage and an imbalance in antioxidant defenses contribute to the complex mechanisms involved in preeclampsia.
Article Abstract
Exclusively occurred during pregnancy, preeclampsia causing complex multisystem disorders that lead to maternal and fetal mortality and morbidity. The major burden in discovering pathogenesis of preeclampsia is still widely noticed. Oxidative stress believed to be one of the major causalin its pathophysiology. Its role on reducing blood perfusion thorugh ischemia results on abnormal placentation. Dysfunction assumed to be caused by oxidative damage and antioxidant defence imbalance as it becoming a central feature in the pathophysiology of preeclampsia. This pathway is widely studied and acknowledged recent years.
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| http://dx.doi.org/10.1016/j.preghy.2014.04.014 | DOI Listing |
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