Aim: To determine the ability of clinical symptoms and laboratory parameters to predict adverse outcomes in HELLP syndrome.
Methods: A retrospective chart analysis of pregnant women diagnosed with HELLP during a 5year (2005-2009) period at a tertiary care perinatal center. The diagnosis of HELLP was based on Sibai's criteria and categorized based on the Mississippi classification. Clinical symptoms and the presence of maternal and fetal adverse events were noted from the records. Receiver operator characteristics, likelihood ratios and adjusted odds ratios were used to determine the predictive ability of clinical symptoms and laboratory parameters.
Results: The medical records of 74 pregnant women with HELLP were analyzed. Any adverse (maternal and/or fetal) event was present in 40 (54.1%, 95% CI: 42.4%, 65.7%) pregnancies with HELLP syndrome in this population. One in four pregnancies with HELLP resulted in an adverse maternal event and 35% of pregnancies with HELLP in an adverse fetal event. There were no maternal deaths in this series and the perinatal mortality rate was 149 per 1000 births. Clinical symptoms or laboratory parameters were not predictive of adverse events.
Conclusions: Further research is needed to identify factors that can predict adverse perinatal outcomes in HELLP.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.preghy.2011.01.008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Relationship Between Trait Mindfulness and Depression Severity Among People With Schizophrenia: The Role of Perceived Public Stigma Toward Mental Illness.
J Am Psychiatr Nurses Assoc
January 2025
Ahmad Rayan, RN, CNS, PhD, Zarqa University, Zarqa, Jordan.
Background: Studies have found that trait mindfulness is associated with lower levels of depressive symptoms among people diagnosed with schizophrenia. Still, the role of the perceived public stigma in this association has yet to be established.
Aims: The purpose of this study was to assess the association between mindfulness and depressive symptoms experienced by people diagnosed with schizophrenia, controlling for the impact of their demographics and their perceived public stigma against mental illness.
Factors, characteristics and influences of the changes of muscle activation patterns for patients with knee osteoarthritis: a review.
J Orthop Surg Res
January 2025
Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
Background: Knee Osteoarthritis (KOA) is a prevalent condition worldwide, significantly diminishing quality of life and productivity. Except for the alignment change, muscle activation patterns (MAP) have garnered increasing attention as another crucial factor contributing to KOA.
Objective: This study explores the factors, characteristics, and effects of MAP changes caused by KOA, providing a neuromuscular-based causal analysis for the rehabilitation treatment of KOA.
Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies.
J Cardiothorac Surg
January 2025
School of Medicine, American University of the Caribbean, Cupecoy, Sint Maarten.
Myocardial Injury after Noncardiac Surgery (MINS) is an increasingly recognized complication that significantly impacts postoperative morbidity and mortality. Characterized by elevated cardiac troponin levels without overt ischemic symptoms, MINS presents a challenge in perioperative care. This review article explores the epidemiology, etiology, and management of MINS, with a particular focus on prevention and the latest management strategies.
View Article and Find Full Text PDFPostural stability measures as diagnostic tools for chronic ankle instability: a comprehensive assessment.
BMC Sports Sci Med Rehabil
January 2025
Department of Physiotherapy, School of Rehabilitation, Tehran University of Medical Science, Enghelab St, Pich-e-Shemiran, Tehran, Iran.
Background: Chronic ankle instability (CAI) is characterized by recurrent sprains and persistent symptoms, which impair postural control. This study evaluates the diagnostic utility of various linear and nonlinear postural stability measures in distinguishing individuals with CAI from healthy controls.
Methods: Postural stability was assessed in 24 participants (12 with CAI and 12 healthy controls) using a force platform under four conditions: hard surface with eyes open, hard surface with eyes closed, soft surface with eyes open, and soft surface with eyes closed.
KaRhab: an international online registry for cardiac rhabdomyomas.
Orphanet J Rare Dis
January 2025
Institute of Human Genetics, Leipzig University Medical Center, Leipzig, Germany.
Background: Cardiac rhabdomyoma (RHM) is considered one of the most frequent benign heart tumors in children. However, encounters with cardiac RHM in clinical practice remain rare. Clinical information is primarily available in the form of single case reports or smaller studies with a shortage of large-scale reviews encompassing a substantial number of cases.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!