Investigation of plasmid-borne AmpC β-lactamase genes in Escherichia coli and Klebsiella spp. revealed blaCMY-2-like genes predominantly in E. coli and blaDHA genes equally distributed between both species. This distribution remained stable over time, but blaACT/MIR-like genes, initially common in Klebsiella spp., were not identified in more recent isolates.
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http://dx.doi.org/10.1016/j.diagmicrobio.2015.06.001 | DOI Listing |
Foods
January 2025
Laboratory of Animal Food Products Hygiene and Veterinary Public Health, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Extended-spectrum-β-lactamase (ESBL) and carbapenemase-producing , and spp. are associated with hospital-acquired infections and are commonly isolated across the poultry food production chain. Comprehensive data regarding the prevalence, spatiotemporal variations, and characterization of β-lactam-resistant bacteria in poultry farms and slaughterhouses is scarce.
View Article and Find Full Text PDFMicrob Drug Resist
January 2025
Department of Medical Microbiology, Ankara University School of Medicine, Ankara, Türkiye.
Colistin- and carbapenem-resistant (ColR CrKp) cause important health problems in pediatric intensive care units (PICUs) due to its ability to harbor multiple resistance genes and spread of high-risk clones. In this study, molecular epidemiological characteristics, transferable resistance genes, and alterations of ColR CrKp isolated from PICU were investigated. Isolates were identified by MALDI-TOF MS, and antimicrobial susceptibility tests were performed using disk diffusion method, gradient strip test, and broth microdilution method.
View Article and Find Full Text PDFTrop Med Infect Dis
January 2025
Department of Laboratory Medicine, Faculty of Medicine, Medical Academy, Lithuanian University of Health Science, Eivenių˛ Str. 2, LT-50161 Kaunas, Lithuania.
Background And Objectives: Due to resistance and the lack of treatment options, hospital-acquired () infections are associated with high mortality. This study aimed to analyze the characteristics of patients with infections caused by multidrug-resistant (MDR) and patients' clinical outcomes as well as determine the risk factors for mortality in a tertiary care teaching hospital.
Materials And Methods: A retrospective cohort study including 196 adult patients with strains isolated from different clinical specimens in the Hospital of the Lithuanian University of Health Sciences in 2016, 2017, 2020, and 2021 was conducted.
BMC Infect Dis
January 2025
Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé, Ouagdougou, 11 BP218, Burkina Faso.
Background: Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-PE), particularly Escherichia coli and Klebsiella pneumoniae, have been consistently associated with treatment failure, high mortality and morbidity. The emergence of carbapenem resistance among ESBL-PE strains exacerbates the antimicrobial resistance. However, data are very limited in developing countries as Burkina Faso.
View Article and Find Full Text PDFJAC Antimicrob Resist
February 2025
Department of Microbiology, Norfolk and Norwich University Hospital, Colney Lane, Norwich, Norfolk NR4 7UY, UK.
Objectives: To characterize resistance rates in urinary tract infections caused by Enterobacterales to first- and second-line antibiotics.
Methods: Positive urine cultures examined by the Eastern Pathology Alliance network from September 2018 to September 2023 were retrospectively analysed. Enterobacterales from non-pregnant adults were included.
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