Malignant eccrine acrospiroma is an infrequent, highly malignant primary skin tumor derived from eccrine sweat glands. Though fine-needle aspiration cytology (FNAC) is a well-established diagnostic tool, but if a skin adnexal tumor or primary skin lesion is suspected clinically, the usual approach is biopsy due to easy accessibility. Being itself rare, cytologic features of this lesion is hardly encountered in case reports. As a result, very little is known about the appearance of adnexal tumors like malignant eccrine acrospiroma on fine-needle aspiration samples. A 50-year-old man presented with swelling in the left axilla, clinically suspected to be a soft tissue sarcoma. Fine-needle aspiration was advised, and a cytological diagnosis of malignant eccrine acrospiroma was rendered which was later confirmed on histological examination. Rapid, accurate diagnosis of these tumors is imperative as they have very poor prognosis and an aggressive course with recurrence and/or metastasis. FNAC plays a decisive and easy diagnostic modality in these unusual, rare cases of highly malignant primary skin tumor, and awareness of the lesions is indispensable in their management.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456892PMC
http://dx.doi.org/10.4103/2229-516X.157173DOI Listing

Publication Analysis

Top Keywords

malignant eccrine
16
eccrine acrospiroma
16
primary skin
12
fine-needle aspiration
12
soft tissue
8
highly malignant
8
malignant primary
8
skin tumor
8
malignant
6
eccrine
5

Similar Publications

A Pediatric Case of Multiple Bilateral Symmetric Eccrine Angiomatous Hamartoma.

Acta Dermatovenerol Croat

November 2024

Prof. Ilke Beyitler, Near East University, Faculty of Medicine, Near East Boulevard, Nicosia, Cyprus;

Eccrine angiomatous hamartoma (EAH) is a rare benign skin neoplasm characterized by an increased size and number of eccrine glands or ducts, along with proliferation of vascular structures in the dermis. This case is unique in its presentation of bilateral symmetrical nodules on both hands and the development of new nodules during puberty. It highlights the need for further research and understanding of this rare condition and its potential progression over time.

View Article and Find Full Text PDF
Article Synopsis
  • Primary cutaneous mucinous carcinoma (PCMC) is a rare skin cancer that primarily develops from eccrine sweat glands, commonly appearing on the head and neck of older adults and often exhibiting slow growth.
  • Although it rarely spreads to other parts of the body, PCMC has a high rate of recurrence, making early and accurate diagnosis through biopsy crucial.
  • A case study of a 77-year-old man highlighted the challenges in diagnosing PCMC, leading to surgical removal and further treatment, ultimately resulting in no signs of recurrence one year later.
View Article and Find Full Text PDF

Pemetrexed is a chemotherapeutic, antimetabolite agent that has been used in oncology to treat diseases such as metastatic non-small cell lung cancer and unresectable malignant pleural mesothelioma. Pemetrexed use may result in pseudocellulitis, which presents as poorly demarcated patches or plaques with erythema, edema, warmth, and tenderness. These lesions can present unilaterally or bilaterally on the lower extremities.

View Article and Find Full Text PDF

Digital Papillary Adenocarcinoma at the Site of 5 Years of Recurrent Paronychia: Case Report and Literature Review.

Case Rep Oncol Med

December 2024

Hand and Upper Extremity Surgery, Barrington Orthopedic Specialists, Schaumburg, Illinois, USA.

Article Synopsis
  • Digital papillary adenocarcinoma (DPA) is a rare and often misdiagnosed malignant tumor, commonly mistaken for benign conditions, leading to delayed diagnosis and treatment.
  • A 57-year-old man with recurrent finger infections was ultimately diagnosed with DPA after a surgical evaluation and biopsy revealed both infection and the tumor, necessitating surgical removal.
  • Accurate diagnosis is vital due to the tumor's tendency for recurrence and metastasis, particularly to the lungs and lymph nodes, and current treatment primarily involves surgical excision with focus on achieving negative margins.
View Article and Find Full Text PDF

[A case report of eccrine porocarcinoma of the shoulder with cervical lymph node metastasis].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

December 2024

Department of Otorhinolaryngology Head and Neck Surgery, China-Japan Friendship Hospital, Beijing100029, China.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!